New Journal Article Published on Migraine

NEWS RELEASE

An article I wrote is in “Article in press” mode publishing on December 1st. Title “Migraine Cause and Treatment” in the Journal of Mental Health in Family Medicine.

Abstract

Migraine Cause and Treatment

Background: Research shows that migraine brains have hyperactive sensory organs and multiple sensory receptor connections. Hyper activity of these organs needs extra supply of nutrition to support increased electrical activity. Today’s medicines reduce or prevent the functioning of these neurons by blocking essential voltage dependent calcium or sodium channel instead of providing nutrients. We asked: if we provide support for extra electrical activity of migraineurs, would it prevent migraines without the use of medicines?

Methods: We reviewed published literature and conducted research over 6 months studying 650 volunteer migraineurs in a migraine-research Facebook group. Participants were screened for migraine types, answered a questionnaire on medical conditions, medicines used, and lifestyle. They were provided instructions on the use of the migraine protocol and were evaluated weekly.

Findings: Migraine frequency appears to be exacerbated by carbohydrate-rich and salt- and water-poor diets and may be worsened by medicines that block voltage gated calcium or sodium channels. Stopping these medicines, reducing carbohydrates and increasing saline in electrolytes appears to prevent and/or stop migraines.

Conclusions: H2O and Na+ efflux from cells caused by glucose, electrolyte mineral (Na+, Cl, K+) ratio may be disrupted in carbohydrate heavy diets causing migraines. Changes to diet that include increased salt intake along with reduced carbohydrate intake appears to prevent glucose induced electrolyte changes which then decreases migraine frequency. In the present study, all participants who made these dietary changes were able to eliminate migraine medications and remained migraine free.

Enjoy reading the full article! I hope to elicit more than usual turmoil since this article goes against all conventional migraine treatments but it actually works and there are no medicines involved. 🙂

Comments are welcome as always!

Angela

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Big Pharma as Organized Crime by Dr. Peter Gøtzsche

Do Drugs Kill Us?

Watch this: Watch this: https://youtu.be/dozpAshvtsA ( post the link and embed, not sure which will work for whom)

I am not even shocked in any sense of the world.

Here is another one that I found just as the first one finished: https://www.youtube.com/watch?v=g8bt8eUB1CU

 

Comments are welcome as always!

Angela

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The McDonaldization of Medicine” Seriously?

Fast Food Method Philosophy = Fast Healthcare Method Philosophy

This is the first time I hear the expression “The McDonaldization of Medicine“. It does not mean what you think it means. It has nothing to do with McDonald’s being unhealthy or healthy or red or blue or yellow. Nope. It is a business model for medicine! It was just published in JAMA Neurology, one of the most prominent medical journals in the world. Coincidentally it published on what has come to be known as National Fast Food Day in the US. Coincidence? Not sure!

In case the link does not open for you, the full citation:

The McDonaldization of Medicine FREE ONLINE FIRST

E. Ray Dorsey, MD, MBA1; George Ritzer, PhD, MBA2
1Department of Neurology, University of Rochester Medical Center, Rochester, New York
2Department of Sociology, University of Maryland, College Park
JAMA Neurol. Published online November 16, 2015. doi:10.1001/jamaneurol.2015.3449

Fast Food versus Healthcare Expectations

While one certainly can and should expect a fast food place to provide fast service at lower price and associated lower quality than what one could eat in a fancy restaurant of higher price, one does not expect the same to be true of medicine or healthcare in general. In medicine, where people’s lives are at stake, one does not expect a business model that follows the fast food model: fast in and out, service quick, cheap, and quantity matters more than quality. Fast foods also have one more business model point that is often overlooked: quantity is more important than quality. Thus if McDonald’s (or any other fast food brand has) say ten thousand customers a day, making ten of them unhappy will not cause harm.

A health institution that sees patients as business revenue is not a health institution but a disease institution. Why? Because making people healthy is bad business! Who needs care when healthy? People need care when they are sick. Thus the McDonadlization (ouch I hate this word) of our healthcare system makes the system into a disease system.

Do we want a disease system to manage our health?

Why would we? That’s like asking the proverbial mouse to stand guard over the proverbial cheese. I am glad I happened to read the JAMA’s today story today totally by accident. Normally articles pile up for me to read but fate brought me in touch with reality: We have been McDonaldized!

So how do we stop this nonsense? By making demands from our doctors! When you have your next visit for whatever reason, tell him or her that you pay for the services received and you have earned the right to the detailed explanations, the exact numbers in print as well so you can go to another doctor and have them explain the same thing and see the conflict! Also, do not forget to check the database to see how much money your doctor has taken from big pharma in 2014! Chances are it will amount to more than $10. If so, be aware that you are money (or food or vacation) in the eye of your doctor and not a patient! Some of my migraine sufferers found doctors who made over $80,000 in 2014 on medicines they prescribed! They have a vested interest in you being McDonalized and that you eat as much junk food as possible.

Oh, and by the way, by junk food I mean the following: sugar, sugar substitutes, fruit juices, fruit and vegetable smoothies, fruit and vegetable shakes, vegetable juices and puree like V8 or tomato sauce, and while we are at it, add to the junk food list all non-fat, low-fat, and reduced low-calorie anything, and vegetable oils as well. If you really want to eat healthy, also add to the list of junk food all grains: bread, pastas, cereal, cakes, biscuits, and whatever is made with them. And to top it all off, put all canned and prepared foods to the list of junk foods!

Now then. Shall we head to the grocery store and shop? We really only have about 4 shelves to use for shopping: dairy (get whole milk, whole yogurt if you find any and with no sugar added, whole milk cheese if you find any (you can’t, so buy not American like Brie), then pick up some heavy whipping cream for extra fat (do not add sugar and do buy a whipping machine for like $15 on amazon or elsewhere! Then grab some lovely cage free grass-fed free range eggs, head to the meat counter and buy some wonderful pasture raised beef with fat, pork, chicken, fish (with skin on and wild caught) and then the produce island to pick up veggies, fruits, and nuts and seeds. If you need oil head for the special oil section of olive, grape seed (love that one!), coconut oil, or use butter.

Done. It was easy! Now you have officially been un-McDonaldized… sheesh… the word is getting worse and worse… But once you have done all these, who needs a doctor? 🙂

Comments are welcome as always!

Angela

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Will a Medicine Help You? The Numbers Will Shock You!

I love TED. I watch TED programs all the time because in 15-20 minutes they summarize important information that you cannot get anywhere else! This TED is like that.

This is the most important TED you may ever watch in your life. Ignore the beginning and the title since while those are funny and nice, the important part of the message actually comes later! I am wondering how the beginning half of the video connects to the second half–I know there is some resemblance in importance and some connection but the important stuff is in the second half.

The important part is about the numbers used to calculate the percentage of how medicines may help or hurt people for whom they are prescribed! The numbers are so amazing that the process will stop you in your track for any medicine you are taking! Of course no doctor will ever tell you these numbers and the statistical test results of adverse reactions that are included with the medicine do not actually portray the real information you need to know.

Since there is a transcript of the TED video is also available, I am grabbing some of the key points for you in case you do not have the 15-20 minutes to watch this awesome video. Also I find that numbers like this look way better in writing than listened to because they have the chance to dig deeper in your brain.

There is a number called NNT.

What is NNT?

NNT is the number of people needed to be treated (by the medicine or surgery or any procedure) in order to claim one person getting any benefit from the treatment and reach the desired “cure” is achieved.

By all of our selfish thinking, this number should be one. Your doctor would not prescribe anything to you that he/she did not think would help you or would s/he?  To your doctor’s excuse s/he may not actually be aware of what NNT is although it was taught in med school at some point! But this is just as easily forgotten as the metabolic consequences of many medicines or even the metabolic pathways and interactions thereby of the many medicines they prescribe. 

NNT

From the transcribed document at the bottom of this video:

GlaxoSmithKline estimates that 90 percent of the drugs work in only 30 to 50 percent of the people. So the number needed to treat for the most widely prescribed statin [cholesterol reduction medicine], what do you suppose it is? How many people have to take it before one person is helped? 300. This is according to research by research practitioners Jerome Groopman and Pamela Hartzband, independently confirmed by Bloomberg.com. I ran through the numbers myself. 300 people have to take the drug for a year before one heart attack, stroke or other adverse event is prevented

“Well, OK, one in 300 chance of lowering my cholesterol. Why not, doc? Give me the prescription anyway.” But you should ask at this point for another statistic, and that is, “Tell me about the side effects.” Right? So for this particular drug, the side effects occur in five percent of the patients. And they include terrible things — debilitating muscle and joint pain, gastrointestinal distress —but now you’re thinking, “Five percent, not very likely it’s going to happen to me, I’ll still take the drug.”But wait a minute..300 people take the drug, right? One person’s helped, five percent of those 300 have side effects, that’s 15 people. You’re 15 times more likely to be harmed by the drug than you are to be helped by the drug.

Medical ethics requires it, it’s part of the principle of informed consent. You have the right to have access to this kind of information to begin the conversation about whether you want to take the risks or not.

…For the most widely performed surgery on men over the age of 50, removal of the prostate for cancer, the number needed to treat is 49. That’s right, 49 surgeries are done for every one person who’s helped. And the side effects in that case occur in 50 percent of the patients.They include impotence, erectile dysfunction, urinary incontinence, rectal tearing, fecal incontinence. (emphasis added)

Thus your chances of recovery from prostate surgery is very slim plus you are 24.5 times more like to have horrible side effects than not.

Looking at it from this perspective, I would demand to see every single medicine’s NNT from my doctor from now on if I were you! I most certainly will. I do not consider myself to be a guinea pig and wish not to be part of any experiment without my expressly asked for and written consent!

Your comments are welcome as always!

Angela

Founder of Stanton Migraine Protocol® and Author of Fighting the Migraine Epidemic and many other books sold worldwide.

Posted in Big Pharma, Drugs of Shame, FDA, Healthcare, Interesting reading, Must Read, Thoughts, Videos | Tagged , , , , , , , , , | 19 Comments

Low Salt for Heart Health? Look Again!

Salt is not the enemy! Sugar is!

Those of you still blaming salt for your high blood pressure, cholesterol deposits and heart problems, look again and empty your fridge! Read this article and start eating and drinking right and yes: increase your salt to normal levels too while at it!!! This is not the first article of this kind. I know you have seen many! But the goal is to drill the routine deeper and deeper until you actually get it and start acting upon it!

Dump Sugar!

Why sugar? Sugar (table sugar, raw sugar, organic sugar, honey, maple syrup, sugar candy at the fair) of any kind breaks down into two parts (simplified here): fructose and sucrose. Sucrose is also of parts (also simplified): fructose and glucose among other things.

Glucose heads straight to your head and makes kids pop off the walls, after which they have a sugar crash and they slump down on the sofa playing games.

Don’t blame them! Blame the sugar!

Fructose is the one that causes problems for your heart. Fructose is not recognized by our body as sugar so it does not spike insulin. Great you think? Think again! The metabolism of fructose is the one that

  1. causes your heart to fail,
  2. causes high cholesterol,
  3. causes metabolic syndrome followed by non-alcoholic fatty liver disease,
  4. causes high blood pressure … and many more bad things

Fructose first converts to ethanol (yep, the stuff mixed with your gasoline for your car) which is an alcohol. Thus though you may never ever drink alcohol, your liver is full of it… so much for having an alcohol free life… lol… all you need is sugar!

The liver then has the job of converting this alcohol into fat. The fat it converts it into is the bad cholesterol, the sticky type LDL that is called triglycerides. The cholesterol buildup in arteries then narrow making the passage of blood hard. This causes blockage that leads to heart attacks. This is all from the sugar caused build-up by triglycerides!

To avoid heart problems and to lower your BP, it is not salt you need to reduce but sugar. So stop eating and drinking sugar in any shape or form.

Sugar substitutes lead to diabetes 2. Your best bet is simply learn to not have something sweet in your mouth at all times!

Also, show this to your doctor on your next visit since he/she will call you a bluff otherwise! MDs have little time to read anything and they still go by the art of medicine they learned in med school however that long ago that was! Teach them what they need to know since this information is new! Chances of them knowing this is pretty slim! So help them!

Comments are welcome as always!

Angela

Founder of Stanton Migraine Protocol® and Author of Fighting the Migraine Epidemic and many other books.

 

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Sugar Podcast!

Sugar Tax like Cigarette or Alcohol Tax!

Listen to this podcast!!! The most important podcast for your health!

Normalize the sugar market

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Where is My Bacon!!

What? Bacon and red meat cause cancer? Just hold that thought!

You may have seen the news coming out yesterday or today that eating bacon and red meat cause cancer. If that scared you, here is an article  shared by a NZ anti-sugar advocate and written by  that is worthy of your time in reading (it is short and she wrote it today specifically in reaction to the news).

My comment to this new cancer discovery is this: Many journal articles miss the importance of (or skilled use of) statistics! I can say that the sales of red cars increased by 10% but unless I say what I compare it with or what year or what model or what country or what on earth, does it have any meaning? Statistics must be looked at in the context of which it was calculated.

I used to reject academic journal articles as a reviewer all the time for mistakes like this but they still always got published because the other 2 reviewers (they usually ask 3 and 2 must agree) had no clue what statistics meant and how to analyze the results. Our society and in fact all societies on this planet are dragged left and right by information that is based on silly and totally incorrect science.

I refuse to be a puppet for clueless scientists even if the WHO (World Health Organization) follows the badly computed analysis! It just makes the WHO as clueless as the rest!

So bacon and red meat? You bet!

Loving every moment of my life and while smoking will kill me, bacon? Not a chance!

Your comments are welcome, as always.

Angela

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Triptans & SSRIs: for Migraines & Depression?

PRESS RELEASE

I wrote an article  as part of the Drugs of Shame series on the many triptans, SSRIs, SNRIs, and similar medicines prescribed for migraines and depressions. I questioned if given all of our new knowledge that both migraines and depression are caused by cortically depressed brain regions (regions not able to generate voltage, which is called “cortical depression”). We also know that voltage applied to those regions stops both migraines and depression by the many deep brain stimulation surgical experiments, as well as by 4000 passing members in my migraine group passing through over the past two years, then why are we using medicines?

I know why: it pays the doctors and the pharmaceutical companies. Check your doctors’ names in this database to see if payments are made–it can say “lunches” or “dinners” but that is since straight payments were knocked to the ground in this open database!

So if you have migraines and/or suffer with depression, I highly recommend you read and share

Triptans ± SSRIs ± Migraines ± Depression: Flip a Coin!

As always, comments are welcome!

Angela

Posted in Big Pharma, Drugs of Shame, Must Read, Press Release | Tagged , , , , , , , , , , , , , , , | Leave a comment

FDA Drug Label Warning Changes

****************IMPORTANT*****************

The MedWatch September 2015 Safety Labeling Changes posting includes 48 products with safety labeling changes to the following sections: BOXED WARNING, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS, or PATIENT PACKAGE INSERT/MEDICATION GUIDE.

The “Summary Page” table provides a listing of product names and safety labeling sections revised:

The following drugs had modifications to the

BOXED WARNING, CONTRAINDICATIONS, WARNINGS AND PRECAUTIONS:

Accupril (quinapril hydrochloride) Tablets
Accuretic (quinapril hydrochloride/hydrochlorothiazide) Tablets
Altace (ramipril) Capsules
Avastin (bevacizumab)
Brilinta (ticagrelor) Tablets
Bydureon (exenatide extended-release) for Injectable Suspension
Cialis (tadalafil) Tablets
Clozaril (clozapine) Tablets
Combivir (lamivudine and zidovudine) Tablets
Doryx (doxycycline hyclate) Delayed-Release Capsules
Epzicom (abacavir and lamivudine) Tablets
Fazaclo (clozapine) Orally Disintegrating Tablets
Gazyva (obinutuzumab)
Humira (adalimumab) Solution
Invokamet (canagliflozin and metformin HCl) Tablets
Invokana (canagliflozin) Tablets
Levitra (vardenafil hydrochloride) Tablets
Myalept (metreleptin) for Injection
Neulasta (pegfilgrastim) Prefilled Syringe/On-body Injector
Neurontin (gabapentin) Capsules, Tablets, and Syrup
Nicorette (nicotine polacrilex) Gum
Nicorette (nicotine polacrilex) Large Lozenge
PegIntron (peginterferon alfa-2b) Injection, for Subcutaneous Use
Proglycem (diazoxide) Capsules and Oral Suspension
Sabril (vigabatrin) Tablet and Powder for Oral Solution
Sancuso (granisetron)
Staxyn (vardenafil hydrochloride) Orally Disintegrating Tablets
Stendra (avanafil) Tablets
Triumeq (abacavir sulfate, dolutegravir, and lamivudine) Tablets
Trizivir (abacavir, lamivudine, and zidovudine) Tablets
Velcade (bortezomib) for Injection
Versacloz (clozapine) Oral Suspension
Viagra (sildenafil citrate) Tablets
Votrient (pazopanib) Tablets
Xalkori (crizotinib)
Zestril (lisinopril) Tablets
Ziagen (abacavir) Tablets and Oral Solution

From now on I will keep all medicine box label updates posted here as well as on my public profile Facebook page for your guidance!

Because some medicines were not listed in the above update for some reason, I decided to paste here the entire list as it appears on the FDA site. Links are included with each medicine; please click and follow!

September 2015

September 2015

Drug Safety Labeling Changes
The summary view includes drug products with safety labeling changes to the BOXED WARNING, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS, or PATIENT PACKAGE INSERT/MEDICATION GUIDE sections. The “quick view” table below provides the drug name and sections modified. Click on the drug name to go to the detailed view. The detailed view includes sections and subsections modified, a description of new or modified safety information in the BOXED WARNING, CONTRAINDICATIONS, or WARNINGS sections, and a link to the revised prescribing information.

Key to Label Section Acronyms:

BW=BOXED WARNING, C=CONTRAINDICATIONS, W=WARNINGS, P=PRECAUTIONS AR=ADVERSE REACTIONS, PPI/MG=PATIENT PACKAGE INSERT/MEDICATION GUIDE

DRUG NAME SECTIONS MODIFIED
(Click on drug name to go to detailed view) BW C W P AR PPI/MG
Brilinta (ticagrelor) Tablets X X
Clozaril (clozapine) Tablets X X X X X
Combivir (lamivudine and zidovudine) Tablets X X X X PCI
Epzicom (abacavir and lamivudine) Tablets X X X X
Fazaclo (clozapine) Orally Disintegrating Tablets X X X
Triumeq (abacavir sulfate, dolutegravir, and lamivudine) Tablets X X X X
Trizivir (abacavir, lamivudine, and zidovudine) Tablets X X X X X PCI, MG
Versacloz (clozapine) Oral Suspension X X X X
Ziagen (abacavir) Tablets and Oral Solution X X X X X PCI
(Click on drug name to go to detailed view) BW C W P AR PPI/MG
Cialis (tadalafil) Tablets

*PDE5 Inhibitors – Increased Risk of Hypotension with Concomitant Use of Guanylate Cyclase Stimulators

X PCI
Levitra (vardenafil hydrochloride) Tablets

*PDE5 Inhibitors – Increased Risk of Hypotension with Concomitant Use of Guanylate Cyclase Stimulators

X PCI
Myalept (metreleptin) for Injection X X X
Staxyn (vardenafil hydrochloride) Orally Disintegrating Tablets

*PDE5 Inhibitors – Increased Risk of Hypotension with Concomitant Use of Guanylate Cyclase Stimulators

X PCI
Stendra (avanafil) Tablets

*PDE5 Inhibitors – Increased Risk of Hypotension with Concomitant Use of Guanylate Cyclase Stimulators

X PCI
Viagra (sildenafil citrate) Tablets

*PDE5 Inhibitors – Increased Risk of Hypotension with Concomitant Use of Guanylate Cyclase Stimulators

X PCI
(Click on drug name to go to detailed view) BW C W P AR PPI/MG
Altace (ramipril) Capsules  X X
Bydureon (exenatide extended-release) for Injectable Suspension X X
Doryx (doxycycline hyclate) Delayed-Release Capsules X X X
Gazyva (obinutuzumab) X X
Humira (adalimumab) Solution X X
Invokamet (canagliflozin and metformin HCl) Tablets X X X
Invokana (canagliflozin) Tablets X X X
Neulasta (pegfilgrastim) Prefilled Syringe/On-body Injector X X
Neurontin (gabapentin) Capsules, Tablets, and Syrup X X X PCI
Proglycem (diazoxide) Capsules and Oral Suspension X X
Sabril (vigabatrin) Tablet and Powder for Oral Solution X X
Sancuso (granisetron) X X
Votrient (pazopanib) Tablets X X X PCI
Xalkori (crizotinib) X X X
Zestril (lisinopril) Tablets X X
(Click on drug name to go to detailed view) BW C W P AR PPI/MG
Accupril (quinapril hydrochloride) Tablets X
Accuretic (quinapril hydrochloride/hydrochlorothiazide) Tablets X
Avastin (bevacizumab) X X
Nicorette (nicotine polacrilex) Gum
Nicorette (nicotine polacrilex) Large Lozenge
X
PegIntron (peginterferon alfa-2b) Injection, for Subcutaneous Use  X
Velcade (bortezomib) for Injection X
(Click on drug name to go to detailed view) BW C W P AR PPI/MG
Breo Ellipta (fluticasone furoate/vilanterol) Inhalation Powder X
Cubicin (daptomycin for injection) X
Depakene (valproic acid) Capsules
Depakene (valproic acid) Oral Solution
Depakote (divalproex sodium) Delayed Release Tablets
Depakote Sprinkle Capsules (divalproex sodium delayed release capsules)
Depacon (valproate sodium) Injection
Depakote ER (divalproex sodium) Extended Release Tablets
X
Eliquis (apixaban) Tablets X
Estring (estradiol vaginal ring) X
Intermezzo (zolpidem tartrate) Sublingual Tablets X
Lastacaft (alcaftadine ophthalmic solution) X
Pradaxa (dabigatran etexilate mesylate) Capsules X
Savaysa (edoxaban tosylate) Tablets X
Temodar (temozolomide) Injection for Intravenous Use X
Xarelto (rivaroxaban) Tablets X
Zioptan (tafluprost ophthalmic solution) X

Questions are always appreciated! Please share so others can benefit from this update!

Angela

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Welcome to Stanton Migraine Protocol Website!

Source: Welcome to Stanton Migraine Protocol Website!

My new website for migraine sufferers who wish private consultation about the Stanton Migraine ProtocolTM

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