Invited Editorial for JACC

Journal of the American College of Cardiology

The Journal of the American College of Cardiology (Elsevier) editors asked me to write an editorial commentary on an academic article that is also going to be published (not written by me) on the association of cardiovascular disease and migraine with aura.

While there is a strong association between migraine with aura and an increase in the risks associated with various cardiovascular diseases, such as strokes, in most scientific literature, this academic article will surprise you! 

My editorial discusses why their findings are what they are. 

My editorial will be published on June 13, 2023. I will update and post a link as soon as it is out. The title is: Are We Sure We Know the Risk Factors for Cardiovascular Disease?

Sorry for MIA otherwise, as you can see, I have been very busy with other things, including creating a lecture on neurology for the Nutrition Network, which will be offered as part of their Neurology module for continuing educational credit for healthcare providers.

I am also working on the final edition of my migraine book (current edition is here) and am hoping to release it early next year.

Comments are welcome, as always, and are moderated for appropriateness,


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Super Migraine Sufferer

What? A Boston Marathon?

The Medal of Completion

Migraineur Runs the Boston Marathon

Angela Stanton I promised I would report on how my marathon went. I ran a 3:16 (7:23 pace per mile). and finished in the top 10% of women at the Boston Marathon, even higher in my age group. It was a tough day. Lots of rain, including hail, wind and hills. It wasn’t my fastest ever time (which is 3:13 from NYC marathon) but I finally finished without nausea, and I don’t feel sore at all. I did feel underfueled during the race and that is going to take some tweaking if I want to get faster.

But I beat 90 percent of women, 99 percent of whom were likely stuffing white carbs the whole weekend. There may be a way to address carb thresholds in the future but for this first go, I am very happy. No edema, no feeling dizzy at the end, no migraine i did drink some seltzer in the finishers chute. Gratuitous photo of the medal. Food was carnivore.

See more testimonials.


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Long Time No Hear

Busy Times!

It’s been awhile that I posted anything new. While I am working on a few things, I thought the least I could do it post the most recent interview links.

In the order of most recent to earlier:

“Fighting the Migraine Epidemic: The Groundbreaking Work of Angela A Stanton, PhD” by Coach Stephen BSc Hons

Interview with Angela Stanton; by Rebekah Farmer


Fabulously Keto by Jackie Fletcher and Louise Reynolds: “127: Angela Stanton – Fighting The Migraine Epidemic

Much more stuff is cooking in the oven.


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New YouTube Interview

A super cool video on just about everything. I hope you enjoy it!

We talk about migraine to start with but soon switch to economics, neuroeconomics, mathematics, and education. Fascinating and highly controversial subject.

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New Alliance with Request A Test

For those who don’t have some/all blood tests covered by insurance or their doctors don’t want to order some tests they wish to have.

Today, November 18, 2022, Request A Test medical testing company released two packages that they created with my recommendation. I designed these specifically for migraine sufferers, although obviously they can be used by anyone.

One of the tests is for the evaluation of all of the vitamins and minerals that can be problems to migraine sufferers. You find this test here. It is a combination of previously available packages and individual tests now bundled into one.

And the other test is a test for cardiovascular health that incorporates insulin and vascular inflammation caused also by homocysteine and not just cholesterol, plus previously available cholesterol tests, like NMR. You can find this test here.

In addition to having these tests available to you, if you are in my migraine group on Facebook, you also receive a discount code.

Join us if you are a migraine sufferer!


Comments are welcome, as always, and are monitored for appropriateness.

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Ketosis & Measuring Ketones Explained

(Image from google)

By Popular Request

Over the years I have been asked several times to discuss ketones (as in ketone bodies), ketosis, and the measurement of ketones or the level of ketosis. The word “ketone” is commonly misunderstood by the public and often misused by commercial interests. In this article I hope to dispel some myths and correct some mistaken ideas, not only in terms of what ketones are but also how we can measure them in our body and what information each measuring method may reveal.

What Are Ketones?

In the above image, which I copied from an academic article over a year ago (no longer remember which one), you can see that there are three types of ketone bodies. These three types are measurable and are the most understood by today’s science.

The picture should be read by starting in the middle top, where you can see “Fatty Acids” that are converted to Acetyl CoA, which then magically appear as Acetoacetate. This process is complex, and I won’t cover it here. Nevertheless, it took us to the first ketone body: Acetoacetate. To the left and right you can see two other ketone bodies, and arrows indicating the direction of the conversion. So, Acetoacetate can convert to Acetone in one direction (to the right), meaning that Acetone cannot convert back into Acetoacetate. Once it is Acetone, that’s it. And if you look in the other direction (left side), you see 3-B-Hydroxybutyrate (BHB) with a double arrow, meaning that when Acetoacetate converts to BHB, it is possible for BHB to convert back into Acetoacetate. This will become important!

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Are We a Generation of the Addicted?

Are Some Foods Addictive?

I ask this question and provide answers in my latest blog article at Hormones Matter. Below a very much shortened version. I hope you read the full article to understand the full concept.

…While we all recognize drugs and alcohol as addictive substances, today, one of the most common addictions is to food, specifically to carbohydrates. Yes, carbohydrates. What is a carbohydrate? It is basically a sugar such as glucose, fructose, and starch. I am sure by now you have heard the news that sugar is addictive, but do you know that there are many foods that are high in carbohydrates that don’t taste sweet at all? For example bread, rice, potatoes, legumes, etc., are full of sugar without tasting sweet. In these foods the sugar is in the form of starches, which are long chains of glucose molecules, but since we lack enzymes that can break these long chains into individual glucose molecules, we don’t taste their sweetness. Yet they are full of addictive sugar…

The Addicted Brain

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Are You A Migraine Sufferer?

All You Need to Know About Migraine:

Watch this video: Angela A. Stanton Ph.D. (me) being interviewed by Florence Christophers at the Kick Sugar Summit in September 2022.

Since this is not a YouTube video, I can only link and cannot embed. Please watch the video here.

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Why I Left Academia

When I started my doctoral dissertation and the associated research, I was absolutely full of love toward what I was doing. I worked on understanding how specific hormones in the brain (neuropeptides) modify human decision-making. I ran clinical trials and published several articles. Here is chapter 2 of my dissertation published in PLOS One. It is one of their top papers in terms of citations. Great stuff! But then the troubles start. You get your PhD and you are on your own.

Publish or Perish

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Depression vs Serotonin “Antidepressants”


An Incredible Find

An amazing statement at the end of the abstract of this article (open access article):

“The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations.”

(Moncrieff, J., Cooper, R.E., Stockmann, T. et al. The serotonin theory of depression: a systematic umbrella review of the evidence. Mol Psychiatry (2022).

And, to make it worse, look at this last sentence:

“Some evidence was consistent with the possibility that long-term antidepressant use reduces serotonin concentration.”

Meaning that when you supplement serotonin, your brain starts making less! This achieves the exact opposite results from what is desired, and this explains why so many people end up taking multiple serotonin medications for depression, which can lead to serotonin syndrome, a killer that killed my mother!

Importantly, migraineurs often end up being placed on antidepressants under the pretense that migraine too is a serotonin deficiency, just like depression. But we know that migraine not a serotonin deficiency. Migraine is a genetic condition caused by various conditions that initiate an electrolyte imbalance and the brain simply ends up running low on salt. The Stanton Migraine Protocol(R) works perfectly for migraine reduction and prevention without the use of any medications.

In fact, since we now understand that if antidepressants are prescribed, the end result is having less serotonin in the brain than what was there before! So what serotonin supplementation achieves is less serotonin made by the brain! The exact opposite of what is intended.

By contrast, there is plenty of anecdotal evidence (counted by the tens of thousands of people by now) whose depression moved to remission when they dropped plants out of their diets and moved to an all animal diet.

Share this article with friends and relatives who are taking antidepressant medications.

Comments are welcome, as always, and are monitored for appropriateness,


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