What Medicines Can Do: Type II Diabetes Anyone?

Adverse Reactions–Do You Recognize Them?

Ah yes, you needed a medicine to make you feel better. We all sometimes end up with medicines though statistically speaking medicines cause more harm than good. While the number of death from heroin, an illegal substance, was under 14,000 people in the US in 2014, in the same year the number of people who died as a result of adverse reaction from prescription medicines was close to 30,000. Medical errors, including the prescription of the wrong medicine or adverse effects from it, represent the third leading cause of death in the US, and many of those go unreported or end up believed to have been caused by natural causes. Some studies claim that the death rates from medical errors, including the wrong prescription medications used, claim over 180,000 lives are lost annually. Even this report is an underestimation because it only includes Medicare findings. If someone dies from the wrong prescription medicine who is not on Medicare, or the hospital does not receive Medicare benefits for care, the death of those is not included in this data. We have a problem.

I think part of the problem is in advertisements. I have a serious problem with the pharmaceutical industry that advertises prescription medicines on television for people who then grow an expectation of receiving the particular medicine from their doctors—regardless if that is a beneficial medicine for them or not! Including medicines for depression or chronic pain.

We outlawed alcohol advertisements on television yet only 2,200 people are reported by the CDC to die in alcohol poisoning annually, quite a bit shy from prescription drug caused death.

Why do we not outlaw prescription drug advertisements?

It would be a logical step to reduce drug awareness of the public and thereby their expectations from their doctors. One of the reasons why antibiotic resistance is so rampant is that people with viral infections, who don’t need antibiotics, consider they received substandard medical care if they don’t receive antibiotics. It is a reverse world where doctors are considered to be substandard if they don’t prescribe medicine.

While most medicine adverse effects are reported to the FDA MedWatch system, either by the patients themselves or responsible doctors, not all people report problems and not all adverse effects are reportable! Some adverse effects you may not realize was caused by a particular medicine you may have taken a month earlier!

The Case of Corticosteroids for Inflammation

Take the case of having to take a corticosteroid medicine (prednisone or prednisolone). It is a medicine that is so frequently prescribed that I don’t even know a single person who has not had to take it at least once in their lives. Of course, a caring physician or pharmacist will explain to take it with food, don’t drink alcohol while taking it, etc. However, here is an adverse effect you probably have never heard of and unless I tell you about it, you never would hear either.

Corticosteroids and Type II Diabetes

Not a typo: taking corticosteroid medicines, like prednisone, can cause type II diabetes. This is not an adverse reaction you will read anywhere and chances of it being reported are pretty much zero since no one will notice! I noticed it by accident! I do not have diabetes of any kind and I am on the ketogenic diet for good health (not weight loss) and migraine-free life. However, I caught a viral bronchitis. Because I also have asthma, I was immediately placed on prednisone.

On the ketogenic diet a person does not eat any sugar or sweets—in my case not even sugar substitutes—and also no fruits or vegetables much since the carbohydrate restriction is great plus I feel way better without any. It is a high fat and moderately low protein diet with minimal carbs if any. I monitor my ketosis level by both urine and blood test to be sure I am within my desired range of nutritional ketosis. I have a sweet spot comfort zone that I wish to stay within, which provides perfect glucose homeostasis. I thus measure my blood glucose—particularly after exercise—to see how much glycogen my liver dumped back into my body for glucose energy (from protein metabolism) so I can return to my homeostasis.

Enter Prednisone

Like glucose, Prednisone (and all steroid medicines) use insulin receptors to be carried around in the body. Since corticosteroid is a very important anti-inflammatory in the body, it has priority over glucose when it comes to insulin. Therefore, all available insulin receptors are tied down with steroid delivery while glucose backs up in waiting. When glucose backs up in your blood, two very important things happen:

1) your brain or muscles are not getting glucose for energy and so the liver keeps on dumping more and more glycogen (glycogen is what the liver saves as glucose for later use) back into your blood as glucose but insulin is not responding. So while you are full of glucose, you are basically starving as far as your brain is concerned!

2) As glucose is backed up, it builds up to considerably high glucose levels (my glucose reader showed 200!) mimicking insulin resistance. Keep this up for longer periods and you will end up with insulin resistance.

As you know, insulin resistance is the hallmark of type II diabetes. Taking steroids for a short course of no more than a 7-day dose pack will not likely to harm you on a regular diet. In my case it did, since I was promptly kicked out of ketosis with the scariest side effects. My blood test for ketosis (measures beta hydroxybutyrate) showed near zero level ketosis but my urine keto strips showed I was in major diabetic acidosis (that can be fatal)! There are no manuals to understand what happened and no adverse reaction report can be made. This is one of those adverse reactions that never show up anywhere and is also not ever told to you by any doctor—if you are lucky enough to find one who is even familiar with the term ketosis.

It sure gave me a great scare and major brain-work to figure it all out. I realized the importance lack of information in deaths caused by prescription medicines! I also recognized that steroids can cause type II diabetes. I know I am not the only one who had to take steroid for a cold for a short duration; I also know people who take steroids for months or years. Workout buffs trying to increase their muscles are in great danger of ending up with type II diabetes. Please tell them!

Comments are welcomed, as always!

Angela

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Tasmania: Cherry Pie to replace Bacon & Eggs?

PRESS RELEASE

Yep, you read that right as silly as it may sound, a city in Tasmania is considering replacing the name of a city from Esplanade Eggs & Bacon Bay to Esplanade Cherry Pie Bay.

The funny thing is that this comes on the hills of the most revealing article in JAMA Internal Medicine about the scam on how the sugar industry formulated the rules of what was to be researched, found, and published, in order to ensure high sales in sugar, even at the detriment of human health and what now has become a global obesity and metabolic syndrome epidemic.  They were (and still are) corrupting all research by not permitting true findings to be published and honest research to be funded.

I wrote an article about the details and in order for you to truly understand what this is all about, you really need to read it here.

Enjoy learning about yet one more corruption revealed and the nutrition industry’s “tobacco industry” like behavior. I can hardly wait when common sense will return and kick academic ego where it belongs–out of academia.

Enjoy the reading and comments are welcome, as always.

Angela

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A Clueless Doctor

The Yelp Review

I keep on posting reviews on Yelp and I find that my negative reviews get removed! So this time I am linking my negative review of this clueless doctor here and am copy-pasting my review. Should Yelp remove it again, I will post it again! Let’s play the game; shall we?

Here is a doctor after whom my blog is named.

“If there was a negative 100* that is what I would write about this doctor. I had a negative review that Yelp removed writing that it is written by a different consumer than who actually had the bad experience. But that is not true. My mother had no idea she had a bad experience with this doctor: I did. Thus all of what I am writing represent my personal opinion and experience and not that of another person.

Two people were affected by this doctor: my mother (now dead as a result of Dr. Heh) and me. So yes, I suppose the primary consumer, my mother, cannot write a review, after all, she is no longer alive, courtesy of the malpractice of Dr. Heh. However, she had no idea about all the damage this doctor was doing so all observations herein are mine.

1) Dr. Heh was the Psychiatrist visiting my mother upon her admittance to St. Jude hospital in 2014 and I was there. On that day, Dr. Heh actually went to the wrong bed and started to interview the wrong patient. When he finally came to my mother, he asked questions from her about her age, gender, home address, etc., all answered correctly. The one question my mom could not answer was what hospital she was in, which is totally expected since she was brought there with an ambulance laying down in dark hours so how would she have known where she was: no one told her. Dr. Heh never ever asked me if my mother had a chance to know where she was; he just “profiled her” based on her age when he misdiagnosed her. I questioned him about his diagnosis since I know my mother had no dementia of any kind. He called me names, he told me to get off whatever drug I was on. He was the most unprofessional doctor I have ever met.

2) Because of my mom did not know which hospital she was in, Dr. Heh decided that my mother (then 88) had Alzheimer’s, which was totally wrong. My mom had serotonin syndrome (I am a doctor so I know) but no one in that hospital gave me any credibility saying that I was not a doctor in “that” hospital therefore whatever I said was gibberish. His treating me–as described in point 1–was very unprofessional plus he was talking to a doctor. He should have known better!

3) After the misdiagnosis and a ton of medicinal mess ups, my mom died about 7 torturous weeks later in a stroke as a direct result of the medicines received based specifically on the diagnosis of Alzheimer’s by this doctor, which she did not have.

4) Upon filing my complaint with the CA Board of Medicine, in spite of the St. Jude records that I have and which shows the date, time and full description of Dr. Heh’s visit with my mom and also half the family in attendance as witness, he, under perjury of oath, claimed that he did not even see my mother. I sent the files back to the CA Board of Medicine, which again wanted to sweep the story under the carpet saying “the case is closed” but I insisted and it is now under investigation. This is a doctor who lies; a doctor who twice entered his visit with my doctor on records (both the same) and which may or may not have been wiped from St. Jude’s records since he is claiming he never saw her, then later he claimed he saw her only in the ER but none of that is true. He is a liar!

5) I sent my mother’s CNS to UCLA for autopsy specifically to see if my mother had any sign of Alzheimer’s in the brain: NONE! I was right all along!

6) I most certainly hope that Yelp will not pull this off again saying that it is not by the consumer this happened to: the actual consumer, my mother, is no longer alive as a result of this doctor so what an unreasonable request! However, much of the interaction of this doctor was with me and against me and so my complaint is double! One that he mistreated my mother and caused her death and two he lied under oath, he called me names and was acting the most unprofessional way.

I hope Yelp this is personal enough for you not to remove it! It is shared on every social media possible as will any changes you make.”

Comments are welcome

Angela

 

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Are You Faking Ketosis?

Fat Burning vs Carbs Burning

As the world turns, we learn more damaging information about how eating grains, highly sugary fruits, and starchy vegetables is bad for us. We learned that foods such as bread, pasta, rice, etc., are basically like eating straight glucose. The amazing damage this misleading information that led the “heart health” fantasy for over 60 years now is over. We now know that obesity, heart disease, metabolic diseases like type 2 diabetes and high blood pressure are all caused by this extremely unhealthy “heart health” hypothesis. Much misleading information is still out there but the new generation of people see past that and there is hope for recovery. However, not everything is rosy.

A large number of people turn to LCHF (low carbs high fat) or ketogenic (even more low carbs and higher fat with moderate protein: no grains, no fruits and only leafy veggies as carbs) or the zero carbs (no fruits, grains or veggies at all just meat and cheese sort of foods), and there are new “fake it to make it” propositions also in abundance. And that is a new generation of bad stuff.

I feel I need to clarify a few things to those of you who want real health and not “fake it” health. After all, what is the point of, for example, getting ketones in your urine if you are really not in ketosis? Who is getting fooled and what is the goal?

To explain what ketones are for those of you who have no idea what I am writing about, here is a very short explanation.

There are two metabolic processes for the human body:

  1. carbs burning (burning glucose for all energy) and
  2. ketones burning (burning fat for all energy with exception of the iris and the cornea of the eyes, that need glucose, which can be derived from protein so there is no need for any carbs).

There is no third metabolic process for humans and there is also no “in between” process either, meaning your body cannot be burning both glucose AND ketones at the same time for energy with efficiency. Protein also becomes glucose and burns as such, hence its limitation in the ketogenic diet, which is a fat burning nutritional approach. While many people use these nutritional approaches for weight loss—hence “diet”—they are actually not for weight loss. That just happens to be a desired benefit.

Here I only want to talk about the basic concepts of carbs burning (regular American diet) versus fat burning (ketogenic diet) to bring home a very important point. The point is: ketones.

Those who eat high fat, moderate protein and very low carbs (understand minimum 80% of your calories coming from fat, about 15% from protein and 5% from carbs maximum), have their bodies switch to fat burning mode. When your body burns fat, it does not burn glucose.

Ketogenic Diet is An Evolutionary Survival tool for Times of Food Scarcity!

The reason why we can burn ketones is important: the ketogenic diet is a nutritional approach for times of starvation, which in human history still happens today. The goal of the body is survival in times of scarcity because we have a huge reserve of body fat and fat per gram gives more than twice the energy of carbs or protein. Thus fat burning is a life-saving procedure our body created for survival.

Can we create ketones in our body without starvation? Sure: eat coconut oil. Eating coconut oil after a slice of cake or just eating it for fun creates ketones similarly to how the body creates ketones in the process of burning body fat in times of scarce food resources. However, just because you ate coconut oil and created ketones, it does not mean your body is burning fat!

Let me repeat: eating coconut oil will produce ketones that show up as ketones in your urine but this does not mean you are in ketosis.

Real ketosis can be used for weight loss and also therapeutic treatment for reversing metabolic diseases such as type 2 diabetes and obesity, and CNS disorders such as seizures, migraines, MS, and potentially other conditions in which neurons have damaged myelination (insulation) from the voltage the brain cells have to pass on. Thus ketogenic diet has health benefits–it is also now used to cure several types of cancer. Ketogenic diet is a serious nutritional tool to achieve a health goal or survive famine!

Ketogenic dieters can use three processes by which they can measure their level of ketogenic progress.

  1. Measure the level of ketones in the urine;
  2. Measure the level of beta hydroxybutyrate in the blood by special blood testing equipment, similar to glucose testing kits,
  3. Use a breath acetone level measuring device.

Of these three, using blood beta hydroxybutyrate is the only accurate measure.

How Urine Ketones Fool You

Ketones in urine are in great numbers until the body doesn’t know how to burn them efficiently. So if you use only urine ketone measuring sticks, your measurement is going to be very misleading. One can measure ketones from eating coconuts or coconut oil (a favorite for ketogenic dieters for some really odd reason!) because coconut can ONLY burn as ketones. One can also measure ketones from forgetting to eat for half a day and while in preparation for some fasting blood test or surgical procedure. Finding ketones in urine does not mean you are in ketosis; it simply means that your body felt some energy crises and started the process of trying to burn fat. The moment you eat after such fasting, carbs burning resumes. You are not in ketosis.

So if you just ate a huge slice of cake followed by a half a watermelon, a soft drink, and a latte with whipped cream (meaning about a half a pound of sugar), and then you take a few coconut oil pills, you will have ketones in your urine! Voila! Fake ketosis!!

If you are a vegetarian or vegan, there is no way on earth you can achieve ketosis while eating only vegetables because all vegetables are carbs (complex carbs but carbs and convert to glucose). However, you sure can fake ketones in your urine. Who are you cheating with that? Yourself, of course.

I have a Marathon runner in my migraine group who is a carbs burner but because of the extreme energy requirements of running a Marathon, midway through the Marathon a runner’s body runs out of carbohydrates and switches to starvation mode, turning on the ketones burning process. In her case I recommended to take with her coconut oil pills for the Marathon and as she felt bonked (out of energy) toward the middle of the run, take coconut oil pills. It helped her then because her body switched to ketones burning and with this help she was able to shave 26 minutes off her best time ever, did not get a migraine, and was not pooped like usual after the run. You can find her story in two parts: part one here and part two here.

This approach is not fake ketosis; this is how to take advantage of ketones when one is not otherwise in ketosis but the body experiences a stress response.

However, if you are a vegetarian or vegan, a major sweet tooth or live off of rice, pasta or any high carbs food, and after eating coconut oil you find ketones in your urine, I have one thing to say: go check your blood! End of faking! Get real! You either take your health seriously or not but if you want to lie to yourself, by all means!

Comments are welcome, as always.

Angela

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How Much Sugar Is In Your Blood?

Hard Time Quitting Sugar?

A little note of interest, especially to those of you having a hard time quitting sugar in any shape or form. I was looking for an article that would explain how much sugar our blood has on average. This is important, because when you eat an apple, you eat approximately 3-5 teaspoons of sugar equivalent but what does that mean to your body? I have been puzzled by that since migraineurs are so sensitive to sugar, and the apple has about 4 teaspoons of sugar equivalent in carbs. What is that relative to the sugar in the blood?

You may be surprised to learn that your blood throughout your entire body of around 5 liters has a grand total of 1 teaspoon of sugar! That is, on average, your entire body has ONE teaspoons of sugar at any given time max–if you are healthy. If it is any higher than that–as fasting–you are prediabetic or have full-blown type 2 diabetes. The difference between being diabetic or normal is very little: instead of 1 teaspoon, make that 1.25 teaspoons!

Yep, a quarter of an extra teaspoon of sugar in your blood means you have type 2 diabetes.

Now let’s put this in the context of a wholesome whole apple of 20-25 gr carbs (pretty average medium size apple) which is 4 teaspoons of sugar equivalent once you subtract the fiber. This 4 teaspoons of sugar is four times as much as what your blood should have in it so your body’s entire focus then is to take all that sugar out and instantly move it to your cells. My most used favorite quote from my medical manual:

“…serum Na+ falls by 1.4 mM for every 100-mg/dL increase in glucose, due to glucose-induced H2O efflux from cells” (Harrison’s manual of Medicine, 18th ed. page 4)

What does this mean? It means that the moment you ate that apple, the glucose kicks sodium (Na+) and (H2O efflux) out of your cells. Where does the sodium and water go you may ask? There are only two locations they can go to:

  1. edema collecting outside of your cells causing swelling, puffy eye lids, swollen ankles and toes, etc,. Usually salt is believed to be responsible for this but it is glucose as you can see.
  2. or the other avenue is to urinate it out.
  3. Because water was removed from your cells you will also feel thirsty but drinking now will just cause more edema or make you urinate more or both.

All of the above happens predictably as my carbs threshold tests in my migraine group shows. Now you face two problems: your blood is full of sugar, your cells are full of sugar and these busted your electrolyte homeostasis, causing insufficient voltage, cortical depression, cortical spreading depression, chronic pain and even aura if your disrupted voltage zone is in the visual cortex and edema plus you urinate clear water. Lovely side effects from eating a healthy apple.

When you eat an apple, you suddenly have several times as much glucose in your blood as normal. Your body needs to move the extra sugar out of your blood very fast so you remain healthy and not diabetic. Eating a single apple will not harm you as long as your insulin is sensitive enough and can take the glucose out of your blood in a timely manner!

Unfortunately, if you are a migraineur, you have a compromised insulin system (1-8). You better watch that apple alone, let alone considering eating or drinking anything else with high sugar content! In the migraine group or under the care of the Stanton Migraine Protocol® you have a solution–come visit to find out what that is.

Did you drink a soft drink or a glass of apple juice?

A soft drink and a glass of apple juice (believe it or not) have about the same amount of sugar because it takes 4-5 apples to make a glass of apple juice. So now you are hit with an amazing amount of sugar your body has to clear. This large amount of sugar is not specific to soft drinks or apple juice: it is also represented by just eating fruits, vegetables, grains, nuts, and seeds. For example, a yellow peach, medium size, is about 3 teaspoons of sugar equivalent; a cup of spaghetti is about 10 teaspoons of sugar equivalent, a small baked Russet potato with skin is about 5 teaspoons of sugar, and one slice of wheat bread is 3 teaspoons of sugar equivalent.

I mention to vegetarians and vegans that their diet is all carbs and they often get very angry at that and feel insulted. They feel they eat the healthiest diet on the planet. I think this needs a bit of explanation! Perhaps the word “carbs” is misleading since they seem to think that carbs = refined sugar but don’t be fooled: every single soil grown plant-based food is made of carbs. Carbs are: glucose, fructose, galactose, lactose, starch, and for total carbs fibers (both soluble and insoluble) are included.

This means that everything that is not fat, animal meat, or fish is carbs.

“Recent surveys suggest that nearly 6 percent of all American men in their fifties suffer from gout, and over ten percent in their seventies. The proportion of women afflicted is considerably less at younger ages but still rises over 3 percent by age 60” (Kramer hm, curhan g, the association between gout and nephrolithiasis: the national health and
nutrition examination survey III. 1988-1994. Am J Kidney Dis 2002;40:37-42)

“One mid-century estimate, for instance, put the incidence of gout in India among “largely vegetarians and teetotalers” at 7%.” (Duncan’s diseases of metabolism, p. 632 (source) (Gout is caused by sugar and not protein is the point here… that part was cut off because that is the entire book chapter from Gary Taubes )

This then explains that:

  1. Your blood does not need that much sugar (made from carbs)
  2. Eating your entire diet in carbs is harmful for you (being vegan is harmful for you)
  3. Don’t drink fruit juices, vegetable juices, nut juices, seed juices, smoothies, shakes, or gels–not even coconut water. If you must eat a fruit, eat it whole with skin and fiber attached.
  4. Your body needs very little sugar—you need not eat any extra! You get too much in your everyday food: I just described here a very partial day for some people who are not even vegetarians or vegans.

Now envision your blood and its gooey sugar content if you eat carbs all day. If you want to fully understand this from an MD’s perspective, read this.

Sources:

  1. Salmasi M, Amini L, Javanmard SH, & Saadatnia M (2014) Metabolic syndrome in migraine headache: A case-control study. Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences 19(1):13-17.
  2. Mohammad SS, Coman D, & Calvert S (2014) Glucose transporter 1 deficiency syndrome and hemiplegic migraines as a dominant presenting clinical feature. Journal of Paediatrics and Child Health 50(12):1025-1026.
  3. Bhoi SK, Kalita J, & Misra UK (2012) Metabolic syndrome and insulin resistance in migraine. The Journal of Headache and Pain 13(4):321-326.
  4. Casucci G, Villani V, Cologno D, & D’Onofrio F (2012) Migraine and metabolism. Neurological Sciences 33(1):81-85.
  5. Sachdev A & Marmura MJ (2012) Metabolic Syndrome and Migraine. Frontiers in Neurology 3:161.
  6. Sinclair AJ & Matharu M (2012) Migraine, cerebrovascular disease and the metabolic syndrome. Annals of Indian Academy of Neurology 15(Suppl 1):S72-S77.
  7. Bhoi S, Kalita J, & Misra U (2012) Metabolic syndrome and insulin resistance in migraine. The Journal of Headache and Pain 13(4):321-326.
  8. Guldiken B, et al. (2009) Migraine in metabolic syndrome. The neurologist 15(2):55-58.

Comments are welcome as always!

Angela

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Master’s in Mechanical Engineering; Stanton Migraine Protocol to the Rescue!

HAPPY NEWS ALERT!!!

Testimonial from a migraineur who just graduated with Master’s degree in Mechanical Engineering! Congratulations to Zofia Kaminski for her achievement and success and may her future job match up to her talent and determination!

Zofia's masters degree

Zofia’s masters degree

Some lucky company that will catch her!❤

I wish Zofia continued migraine free life using the Stanton Migraine Protocol® staying migraine and medicine free!

Angela

Posted in Healthcare, Interesting reading, Migraine-Blog, Must Read, Press Release, This & That, Thoughts | Tagged , , , | Leave a comment

Death Rate and Salt Relation

A graph for discussion

Hypertensive vs Healthy death from salt

Hypertensive vs Healthy death from salt

Posted in This & That | Leave a comment

Act Now! FDA Comment Period on Dietary Sodium!

The FDA is Doing it Again!

As if they had nothing better to do, now it is dietary sodium decrease… again! After hundreds of academic articles show that the more dietary salt we consume, the healthier we are, they want to reduce it.

Salt does not increase blood pressure but sugar does. Why are they not reducing sugar? Ahhhhhhh… money of course… at the same time we all get sick from eating too much sugar because SUGAR increases blood pressure, increases your bad cholesterol and triglycerides, causes a host of other problems–including taking a huge role in dementia, Alzheimer’s, and so forth. You find my comment below that I just filed at the FDA a minute ago, including all references to everything I just said.

Please comment at the FDA as well to make sure that the government starts to focus on what makes us sick! I copy-pasted my comment below; feel free to use any part of it for your quick comment. The link where to comment: https://www.regulations.gov/docket?D=FDA-2014-D-0055

Your comment must be short and sweet (hence I used & and not “and”, etc.,); it cannot exceed 5000 characters.

My comment:

Dear Committee,

Dietary sodium reduction causes harm to the healthy and the hypertensive(1). Migraineurs benefit from higher sodium(2). Sugar increases BP(3-7). Salt is an essential mineral that human cells have many channels for. Dietary sodium increase modifies BP by only a few systolic points (2-6), quite insignificant(8).

The balance of K+ to Na+ ratio is more important to cardiac health than Na+(9-12) & is vital to electrolyte homeostasis – Medline: https://medlineplus.gov/fluidandelectrolytebalance.html.

Hydration is vital to cognition (13-19). Hydration is salt & water. Drinking water alone dilutes electrolytes, causing diseases.

BP increases from sugar; shouldn’t the Committee focus on sugar reduction (3, 20-26)? The Committee should reconsider & focus on CHD & high BP reduction by the substance that causes both: sugar.

Sincerely,
Angela A Stanton, Ph.D.

  1. Mente A, et al. (Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. The Lancet.
  2. Pogoda JM, et al. (2016) Severe Headache or Migraine History Is Inversely Correlated With Dietary Sodium Intake: NHANES 1999–2004. Headache: The Journal of Head and Face Pain:n/a-n/a.
  3. DiNicolantonio JJ & Lucan SC (2014) The wrong white crystals: not salt but sugar as aetiological in hypertension and cardiometabolic disease. Open Heart 1(1):e000167.
  4. Alderman MH & Cohen HW (2012) Dietary Sodium Intake and Cardiovascular Mortality: Controversy Resolved? American Journal of Hypertension 25(7):727-734.
  5. DiNicolantonio JJ, et al. (Dietary Sodium Restriction: Take It with a Grain of Salt. The American Journal of Medicine 126(11):951-955.
  6. Dong J, Li Y, Yang Z, & Luo J (2010) Low Dietary Sodium Intake Increases the Death Risk in Peritoneal Dialysis. Clinical Journal of the American Society of Nephrology : CJASN 5(2):240-247.
  7. Konerman MC & Hummel SL (2014) Sodium Restriction in Heart Failure: Benefit or Harm? Current treatment options in cardiovascular medicine 16(2):286-286.
  8. Stanton AA (2016) Are Statistics Misleading Sodium Reduction Benefits? Journal of Medical Diagnostic Methods 5(1).
  9. Perez V & Chang ET (2014) Sodium-to-Potassium Ratio and Blood Pressure, Hypertension, and Related Factors. Advances in Nutrition 5(6):712-741.
  10. Zhang Z, et al. (2013) Association between Usual Sodium and Potassium Intake and Blood Pressure and Hypertension among U.S. Adults: NHANES 2005–2010. PLoS ONE 8(10):e75289.
  11. Rodrigues SL, et al. (High potassium intake blunts the effect of elevated sodium intake on blood pressure levels. Journal of the American Society of Hypertension 8(4):232-238.
  12. Weaver CM (2013) Potassium and Health. Advances in Nutrition: An International Review Journal 4(3):368S-377S.
  13. El-Sharkawy AM, Sahota O, Maughan RJ, & Lobo DN (2014) The pathophysiology of fluid and electrolyte balance in the older adult surgical patient. Clinical Nutrition 33(1):6-13.
  14. MD KB (2015) Water, Energy, and the Perils of Dehydration. (internet).
  15. Thornton SN (2010) Thirst and hydration: Physiology and consequences of dysfunction. Physiology & Behavior 100(1):15-21.
  16. Popkin BM, D’Anci KE, & Rosenberg IH (2010) Water, Hydration and Health. Nutrition reviews 68(8):439-458.
  17. Armstrong LE (2012) Challenges of linking chronic dehydration and fluid consumption to health outcomes. Nutrition Reviews 70(suppl 2):S121-S127.
  18. Ritz P & Berrut G (2005) The Importance of Good Hydration for Day-to-Day Health. Nutrition Reviews 63:S6-S13.
  19. Benton D (2011) Dehydration Influences Mood and Cognition: A Plausible Hypothesis? Nutrients 3(5):555-573.
  20. Badar VA, Hiware SK, Shrivastava MP, Thawani VR, & Hardas MM (2011) Comparison of nebivolol and atenolol on blood pressure, blood sugar, and lipid profile in patients of essential hypertension. Indian Journal of Pharmacology 43(4):437-440.
  21. Ha V, et al. (2013) Fructose-Containing Sugars, Blood Pressure, and Cardiometabolic Risk: A Critical Review. Current Hypertension Reports 15(4):281-297.
  22. He F & MacGregor G (2015) Salt and sugar: their effects on blood pressure. Pflügers Archiv – European Journal of Physiology 467(3):577-586.
  23. Jayalath VH, et al. (2014) Total Fructose Intake and Risk of Hypertension: A Systematic Review and Meta-Analysis of Prospective Cohorts. Journal of the American College of Nutrition 33(4):328-339.
  24. Kim YH, Abris GP, Sung M-K, & Lee JE (2012) Consumption of Sugar-Sweetened Beverages and Blood Pressure in the United States: The National Health and Nutrition Examination Survey 2003-2006. Clinical Nutrition Research 1(1):85-93.
  25. Nichols H (2015) More than salt, sugars may contribute to high blood pressure.
  26. Sharma N, et al. (2008) High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets. Journal of hypertension 26(7):1402-1410.

Your Comment Tracking Number: 1k0-8rej-ue25 (this is my proof so don;t use this number).

Thanks for your help!

Comments are welcome, as always.

Angela

 

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Quinolone Antibiotics — Black Box Released!

Thank You FDA!

Finally, the long-awaited changes are beginning to be made. Not all quinolones are black-boxed but the most dangerous ones are. In case you have no idea what this is about, search my blog posts for the past 2 years and you will find dozens. I was one of many (I assume many) who filed a petition with the FDA for the removal of these antibiotics for easy prescription for simple infections that can be treated with other antibiotics effectively and to leave these only when all else fails.

Hundreds of thousands (if not millions) of people have been “floxed.” Being “floxed” can mean permanent life-long debilitating health condition that sent some people to commit suicide–you can find one blog post on saying good-bye to one among my posts.

The problem: Quinolones damage bacterial DNA, which is great, except that in every cell we have hundreds of thousands mitochondria–in brain cells millions. Mitochondria are a symbiotic bacteria that provides all energy we have. Without mitochondria we die.

Quinolones Damage Mitochondrial DNA!

While DNA mutates all the time and random disadvantageous changes happen regularly, each change is different and so if a mitochondria is damaged and cannot function, it is ordered to commit apoptosis (cell suicide); problem solved. A secondary–and perhaps bigger–problem is that mitochondrial DNA has no “junk DNA” from which repair can be made. Unlike standard human cell DNA that has a lot of chance for repair from taking what’s needed from the junk DNA to fix the problem in the next mutation, the DNA of the mitochondria is fully used so the chances of a fix by using an unused DNA to mutate and replace the bad one is zero.

This means that affected cells with lots of DNA damaged mitochondria die. There are many types of damages that can happen but the most common ones are:

  • Torn Achilles tendon – I had this and find that the “tendon problem” does not stop at the Achilles nor does it have to be torn to become painful or non-functional. You may experience a modified tendon, something I call “jumping tendons” in which the tendon becomes similar to a rubber band. I have it–so far only–on one finger and let me tell you, it is not fun! Because it can happen anywhere in the body, the warnings on the new label are now modified to Tendinitis and tendon rupture meaning precisely that it can happen anywhere in your body.
  • Occipital neuralgia – damage to the nerve going from your eye(s) to the visual cortex (back of the brain). The damage, if permanent and it usually is from Quinolones, leads to blindness with pain. It is a chronic pain that can sometimes be helped by nerve block injections–something I do not wish on my enemies (well.. maybe).
  • Full body neuralgia (also called Peripheral neuropathy) – same as with the eye(s) only envision that all over your body… need I say more…

To be sure you have the full list of the quinolones you must avoid at all cost unless your life is dependent upon it, here are the ones most commonly prescribed:

  • ciprofloxacin (CIPRO, CILOXAN)
  • enoxacin (PENETREX)
  • levofloxacin (LEVAQUIN)
  • moxifloxacin (AVELOX)
  • norfloxacin (NOROXIN, CHIBROXIN)
  • ofloxacin (FLOXIN, OCUFLOX)

Here is the link to the general medicine label updates but this list includes drugs other than quinolones, so be sure to click on the link of any one to see the new warning. I am also copy-pasting a partial label-change here on Cipro alone, since that monster has been used the most for the smallest infections but the rest of the quinolones have all been updated similarly (see the original here):

BOX WARNING (revised)

WARNING: SERIOUS ADVERSE REACTIONS INCLUDING TENDINITIS, TENDON RUPTURE, PERIPHERAL NEUROPATHY, CENTRAL NERVOUS SYSTEM EFFECTS AND EXACERBATION OF MYASTHENIA GRAVIS

  • Fluoroquinolones, including CIPRO®, have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together including:
    • Tendinitis and tendon rupture
    • Peripheral neuropathy
    • Central nervous system effects
  • Discontinue CIPRO immediately and avoid the use of fluoroquinolones, including CIPRO, in patients who experience any of these serious adverse reactions. Fluoroquinolones, including CIPRO, may exacerbate muscle weakness in patients with myasthenia gravis. Avoid CIPRO in patients with known history of myasthenia gravis.
  • Because fluoroquinolones, including CIPRO, have been associated with serious adverse reactions, reserve CIPRO for use in patients who have no alternative treatment options for the following indications:
    • Acute exacerbation of chronic bronchitis
    • Acute uncomplicated cystitis
    • Acute sinusitis

WARNINGS AND PRECAUTIONS

Disabling and Potentially Irreversible Serious Adverse Reactions Including Tendinitis and Tendon Rupture, Peripheral Neuropathy, and Central Nervous System Effects (addition)
  • Fluoroquinolones, including CIPRO, have been associated with disabling and potentially irreversible serious adverse reactions from different body systems that can occur together in the same patient. Commonly seen adverse reactions include tendinitis, tendon rupture, arthralgia, myalgia, peripheral neuropathy, and central nervous system effects (hallucinations, anxiety, depression, insomnia, severe headaches, and confusion). These reactions can occur within hours to weeks after starting CIPRO. Patients of any age or without pre-existing risk factors have experienced these adverse reactions.
  • Discontinue CIPRO immediately at the first signs or symptoms of any serious adverse reaction. In addition, avoid the use of fluoroquinolones, including CIPRO, in patients who have experienced any of these serious adverse reactions associated with fluoroquinolones.
Tendinitis and Tendon Rupture replaces Tendinopathy
  • Fluoroquinolones, including CIPRO, have been associated with an increased risk of tendinitis and tendon rupture in all ages. This adverse reaction most frequently involves the Achilles tendon, and has also been reported with the rotator cuff (the shoulder), the hand, the biceps, the thumb, and other tendons. Tendinitis or tendon rupture can occur, within hours or days of starting CIPRO, or as long as several months after completion of fluoroquinolone therapy… Tendinitis and tendon rupture can occur bilaterally.
  • The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. Other factors that may independently increase the risk of tendon rupture include strenuous physical activity, renal failure, and previous tendon disorders such as rheumatoid arthritis. Tendinitis and tendon rupture have also occurred in patients taking fluoroquinolones who do not have the above risk factors. Discontinue CIPRO immediately if the patient experiences pain, swelling, inflammation or rupture of a tendon. Avoid fluoroquinolones, including CIPRO, in patients who have a history of tendon disorders or have experienced tendinitis or tendon rupture.
Peripheral Neuropathy (new sentences added)
  • Fluoroquinolones, including CIPRO, have been associated with an increased risk of peripheral neuropathy. Cases of sensory…
  • …minimize the development of an irreversible condition…Avoid fluoroquinolones, including CIPRO, in patients who have previously experienced peripheral neuropathy.

ADVERSE REACTIONS

The following serious and otherwise important adverse drug reactions are discussed in greater detail in other sections of labeling:

  • Disabling and Potentially Irreversible Serious Adverse Reactions (addition)

  • Tendinitis and Tendon Rupture (replaces Tendon Effects)

Please add these drugs on your allergy list and inform your doctor that you refuse to take these!

Comments are welcome as always!

Angela

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Recommending Low Carbs by an MD is Not Permitted!

I am not the only one fighting for health!

This is how far we have come! An MD is not permitted to recommend a low carbohydrate diet for his type 2 diabetic patients!!!

Take a second look at what I just wrote: type 2 diabetes is caused by the inability of the body to process carbohydrates as a result of a compromised insulin system. The treatment is obviously to stop eating sugary fructose filled high sugary foods like juices, cakes, sweets of any kinds. In other words, high fructose implies “refined sugar” or “high sugar natural foods” in any shape and form. Yet in Australia a doctor is now banned from being able to advise his patients from reducing their carbohydrates by eliminating those with high non-essential sugars.

I have been writing now many times about how misled we had been over the past 80+ years and indeed, up until 30 years ago, diabetics (type 2) were actually recommended to increase their carbs (read Gary Taubes) but one would think that in 2016 we have become smarter than that! Apparently political interest trumps the health of people everywhere.

This is a grassroots movement; get on board!

I am copy-pasting this important story from a Facebook page that is now run by the doctor’s wife Belinda Fettke

Belinda Fettke No Fructose

No Fructose

No Fructose

Who can actually give nutritional advice?

My husband, Dr. Gary Fettke No Fructose, has been silenced and so, from today, this page will become Belinda Fettke No Fructose

There has been an AHPRA [Australian Health Practitioner Regulation Agency] investigation into Gary’s qualifications to give nutritional advice and speak on the science of what we eat and its central role in our health. This investigation has been going on for over 2 years and a ‘caution’ has been proposed. Until the case is finalised he will have to abide by the law to maintain his professional registration, and to come back another day.

The Medical Board of Tasmania under the umbrella of the Australian Health Practitioners Regulatory Authority have advised him, ”In particular that he does not provide specific advice or recommendations on the subject of nutrition and how it relates to the management of diabetes or the treatment and/or prevention of cancer.”

Gary is not allowed to comment on the central role of nutrition in preventative health, nor in the management of chronic illness on any social media platform.

Gary has been silenced and cannot discuss nutrition with his patients in any clinical setting, regardless of any undue stress on joints before replacement, inflammation, or even diabetes complications requiring amputation.

Gary is not allowed to speak at any public or professional meetings that involve the discussion of nutrition.

It is IMPORTANT to note: Gary has NOT BEEN CAUTIONED on what he has been advocating with regards to LCHF – Low Carbohydrate Healthy Fat living, nor in regards to lowering carbohydrate intake in diabetes management.

Gary has not been cautioned on what he has been advocating with regards to considering the health benefits of real food that is fresh, seasonal and local.

Gary has not been cautioned on what he has been advocating with regards to the central role of nutrition in health.

Gary has, however, been criticised that his interpretation of his ‘research into a topic’ is not the same as AHPRA’s.

Gary will be questioning the proposed ‘caution’ but until there is a final finding from AHPRA he will have to abide by the law and not communicate on Social Media and by inference, to his patients. That will be difficult for him as he sees the benefits every working day for his patients that adopt better eating habits.

This scenario has been similar to the case of Professor Tim Noakes in South Africa. Tim and Gary have been communicating regularly. The difference between the cases is that Gary has been judged behind closed doors and Tim’s has been in courtrooms.

Gary’s investigation was the result of an anonymous notification and throughout the process he remains unaware of the peers that are judging him. It seems a strange system, where you are guilty until proven innocent, but he hopes to have the opportunity to make representation at some time before the final judgement.

Unfortunately, at this time, AHPRA have determined that Gary, as a doctor must not continue to question the paradigm in an open forum. It won’t stop him researching though, and strengthening his knowledge base.

It concerns me that all manner of people can give advice on the internet, and by definition, I have become one of them.

I have been on this journey with Gary and have my own opinion on matters related to health. By qualification to comment, I have none. My previous work as a Registered Nurse is unlikely to give me any expertise, but, like so many people living the LCHF life, I have seen the benefits in myself and those around me for many others who have decided to Choose Health.

So, if you are interested in helping me continue to question the science, promote the role that Low Carb Healthy Fat principles play in both the management and the prevention of disease, and would like to help me be to become louder than ever before, please join me as the voice of No Fructose.

Remembering that it is now my voice, anything written/said is not to be taken as individual advice for health conditions. I would always encourage you to see your doctor or health professional to individualise treatment and lifestyle advice.

http://www.nofructose.com will similarly be taken over by me🙂

My Declaration of Interest – I am the very proud Co-founder of Nutrition for Life in Tasmania. We offer face to face appointments at our clinics in both Launceston and Hobart, and regularly Skype clients in rural Tasmania and Interstate. We have the most amazing team of health professionals and support staff, and they are making a difference in people’s lives.

If you agree that this is totally wrong, follow the movement and do whatever you can to advance science by opening a few ears and removing some blinders! We are ready for getting our lives back healthy and not artificially being kept ill so we can take more drugs!!

Comments are welcome and sharing this page is highly appreciated!

Angela

Posted in Big Pharma, Healthcare, Interesting reading, Must Read, This & That, Thoughts | Tagged , , , , , , , , , , , , , , | 2 Comments