There is much confusion about migraines among those who have migraines. Some have symptoms a-c, others from b-f and some from y-z. There are some commonalities in all migraines; that we already know. But the symptoms vary among people and may also change over time within the same person experiencing them. Some of the medications used to treat migraine pain (particularly tryptans) affect the nervous system because they are either blocking the making of or blocking the “stop making” signal to reach the neurons’ receptors that naturally manufacture the neurotransmitter serotonin. Serotonin is biochemically derived from tryptophan so in taking drugs that modify the neurons’ ability to make the normal levels of serotonin, the chemical nature of the brain and the entire nervous system changes.
Serotonin is located also in the human gut, aiding digestion by regulating intestinal movement, so you can imagine what games that plays on one’s body to add more or take some away! It is a dangerous medication family. Serotonin has little to do with being a pain killer: “Serotonin’s presence in insect venoms and plant spines serves to cause pain, which is a side effect of serotonin injection. Serotonin is produced by pathogenic amoebae, and its effect on the gut causes diarrhea”. (Wikipedia, Serotonin).
Here is a video (only 3 minutes) that explains a little bit about migraines and the difficulty of even recognizing what is a migraine and what is not. I hope it will help you understand a little more about migraines.
You can find the original posting of this article at my migraine-book.com website under blogs.