Definition of Migraine

I wrote up a short summary of what migraine is, how to diagnose it properly, and how to treat and prevent it. The article is aimed at helping healthcare professionals learn what it truly is, because all they do now is prescribe medications, which is not helpful.

Read the whole article, here is the intro:

Definition of Migraine

Migraine is a genetic condition. Migraine brain has hypersensitive sensory neurons, more sensory neuronal connections, and different electrical properties than a typical brain(1,2). Migraineurs waste 50% more sodium in their urine than typical subjects(3). The most prominent migraine related genetic variants are associated with critical ionic channels that operate the brain’s electrical functions: action potential, resting potential, the delivery of neurotransmitters, and the resetting of the membrane potential(4,5). Migraineurs’ brains are very sensitive to electrolyte imbalance as a result of channelopathy(6-9). Migraineurs tend to end up with metabolic syndrome because of their carbohydrate sensitivity.

Read the rest

Comments are welcome, as always, and are moderated for appropriateness


About Angela A Stanton, Ph.D.

Angela A Stanton, PhD, is a Neuroeconomist focusing on chronic pain--migraine in particular--physiology, electrolyte homeostasis, nutrition, and genetics. She lives in Southern California. Her current research is focused on migraine cause, prevention, and treatment without the use of medicine. As a forever migraineur from childhood, her discovery was helped by experimenting on herself. She found the cause of migraine to be at the ionic level, associated with disruption of the electrolyte homeostasis, resulting from genetic variations of all voltage dependent channels, gates, and pumps (chanelopathy) that modulate electrolyte mineral density and voltage in the brain. In addition, insulin and glucose transporters, and several other variants, such as MTHFR variants of B vitamin methylation process and many others are different in the case of a migraineur from the general population. Migraineurs are glucose sensitive (carbohydrate intolerant) and should avoid eating carbs as much as possible. She is working on her hypothesis that migraine is a metabolic disease. As a result of the success of the first edition of her book and her helping over 5000 migraineurs successfully prevent their migraines world wide, all ages and both genders, and all types of migraines, she published the 2nd (extended) edition of her migraine book "Fighting The Migraine Epidemic: Complete Guide: How To Treat & Prevent Migraines Without Medications". The 2nd edition is the “holy grail” of migraine cause, development, and prevention, incorporating all there is to know. It includes a long section for medical and research professionals. The book is full of academic citations (over 800) to authenticate the statements she makes to make it easy to follow up by those interested and to spark further research interest. It is a "Complete Guide", published on September 29, 2017. Dr. Stanton received her BSc at UCLA in Mathematics, MBA at UCR, MS in Management Science and Engineering at Stanford University, PhD in Economics with dissertation in neuroscience (culminating in Neuroeconomics) at Claremont Graduate University, fMRI certification at Harvard University Medical School at the Martinos Center for Neuroimaging for experimenting with neurotransmitters on human volunteers, certification in LCHF/ketogenic diet from NN (Nutrition Network), certification in physiology (UPEN via Coursea), Nutrition (Harvard Shool of Public Health) and functional medicine studies. Dr. Stanton is an avid sports fan, currently power weight lifting and kickboxing. For relaxation (yeah.. about a half minute each day), she paints and photographs and loves to spend time with her family of husband of 45 years, 2 sons and their wives, and 2 granddaughters. Follow her on Twitter at: @MigraineBook, LinkedIn at and facebook at
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2 Responses to Definition of Migraine

  1. Micki Jacobs says:

    My young daughter suffered migraines until her hypothyroidism was diagnosed and treated.
    She was in elementary school, very thin, and was unable to tan. I joked that she moved so quickly, the sun couldn’t catch her. She was thin, very white, a great student, with extremely dry skin who had ‘slightly on the higher side’ TSH.
    Long story short… endocrinology is absolutely full of it, the bases for diagnosing hypothyroidism are misguided, as are ideas to treat.
    I could go on and on, but for over 20 years I’ve researched this topic and it’s led to connecting many diseases. Modern medicine is incredibly misguided.
    We are starving, poisoned and this eludes all the stinking experts out there.

    Liked by 1 person

    • Micki, I agree that “We are starving, poisoned and this eludes all the stinking experts out there” as you wrote, with one caveat. I don’t think it eludes them. There is a huge financial incentive to stuffing us with foods that starve our body for nutrients because they sold for a lot of money a bunch of nonsense that cost them pennies.

      Take cereals, for example. Cereal was invented by Kellogg in order to reduce his sexual urges–you can look this up anywhere.

      And what is our dietary guide telling us? To eat cereal and similar grain-based foods as the base of our diet, forming the majority of what we eat!

      So do we have a bunch of stupid experts out there? Or doo we have a system of monetary reward based on sick people? I think it is purely financial. If we are all healthy, what do we have all the doctors for? What would big pharma live on if we didn’t need to take medicines?

      People are very easy to mislead. I see this every day! All kinds of nutritional agendas, from vegan to Mediterranean, to Blue regions or low salt: all fake and all designed to force people into nutritional tragedies that won’t make anyone healthy but will keep a dirty-business industry up and running.

      “Modern medicine is incredibly misguided” you wrote but I think there is no modern medicine. What we have is disease management rather than healthcare and all medicines are customized to make us feel better as we are getting sicker. Modern medicine is really not medicine but symptom treatment. There is nothing “medicine” about it other than us popping pills.


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