The long-awaited story about my work on migraine prevention is published on the website of Keto-Mojo. Keto-Mojo is a California company that a few years ago started to sell an excellent quality blood glucose and blood ketones (beta hydroxybutyrate or BHB) testing kit. When I first heard about Keto-Mojo–frankly I no longer remember where I heard of them–I already owned every single type of blood glucose and BHB testing kit available in the US.
I found all of them unreliable and only one (at that time) was designed to use one testing unit for both glucose and BHB testing strips. All the rest needed two separate testing kits. With Keto-Mojo in hand, all of those went into storage for a rainy day. Since my first use of Keto-Mojo, I have recorded over 2000 test results, which have been critical to my understanding of how glucose and ketones work in our body, and what the measured values actually mean.
I have come to different conclusions from what is in general knowledge. This will be the main topic of my upcoming book on ketosis–not the ketogenic diet specifically but all ways of eating that may lead to ketosis.
The Keto-Mojo article is long–migraine cause and process is explained deeply. It also details the prevention process. To see the full protocol in action, please join the protocol group here and the keto group here. Here is a snippet of information about the protocol group, which is extremely active. Below is November 2019 information exchange in the group: over 9000 comments and over 50,000 reactions to comments. A very busy group!
Protocol Group November Group Member Interactions
My current migraine book title is incomplete on the Keto-Mojo blog; it is missing the words “Complete Guide” (this is the 2nd edition), which can be purchased most everywhere in the world, though in e-book format only on amazon.
Fighting the Migraine Epidemic: Complete Guide
The book in the US can be purchased here.
Please read it if you are a migraine sufferer and share this and/or the Keto-Mojo article if you know migraineurs. It will change their lives for the better if they decide to test what I do. The article also talks about “why me” and how I got to do my research. My educational background is also detailed–something you may find interesting and certainly very different.
Why is all this on Keto-Mojo website? I use Keto-Mojo and recommend it to all my migraineurs, so my migraineurs (many thousands) represent a large client-base. Keto-Mojo is the most accurate blood glucose and blood ketones measuring kit available in the market today. It is also available internationally, which is very important to me, since a large percent–about 20-30%–of the migraine sufferers in my groups are not from the US.
I hope you enjoy reading my story, my education and how it connected to my migraine research, and the cause and prevention of migraines.
If you wish to contact me, please send an email via the contact form.
About Angela A Stanton, Ph.D.
Angela A Stanton, PhD, is a Neuroeconomist focusing on chronic pain--migraine in particular--physiology, electrolyte homeostasis, nutrition, and genetics. She lives in Southern California. Her current research is focused on migraine cause, prevention, and treatment without the use of medicine. As a forever migraineur from childhood, her discovery was helped by experimenting on herself. She found the cause of migraine to be at the ionic level, associated with disruption of the electrolyte homeostasis, resulting from genetic variations of all voltage dependent channels, gates, and pumps (chanelopathy) that modulate electrolyte mineral density and voltage in the brain. In addition, insulin and glucose transporters, and several other variants, such as MTHFR variants of B vitamin methylation process and many others are different in the case of a migraineur from the general population.
Migraineurs are glucose sensitive (carbohydrate intolerant) and should avoid eating carbs as much as possible. She is working on her hypothesis that migraine is a metabolic disease.
As a result of the success of the first edition of her book and her helping over 5000 migraineurs successfully prevent their migraines world wide, all ages and both genders, and all types of migraines, she published the 2nd (extended) edition of her migraine book "Fighting The Migraine Epidemic: Complete Guide: How To Treat & Prevent Migraines Without Medications". The 2nd edition is the “holy grail” of migraine cause, development, and prevention, incorporating all there is to know. It includes a long section for medical and research professionals. The book is full of academic citations (over 800) to authenticate the statements she makes to make it easy to follow up by those interested and to spark further research interest. It is a "Complete Guide", published on September 29, 2017.
Dr. Stanton received her BSc at UCLA in Mathematics, MBA at UCR, MS in Management Science and Engineering at Stanford University, PhD in Economics with dissertation in neuroscience (culminating in Neuroeconomics) at Claremont Graduate University, fMRI certification at Harvard University Medical School at the Martinos Center for Neuroimaging for experimenting with neurotransmitters on human volunteers, certification in LCHF/ketogenic diet from NN (Nutrition Network), certification in physiology (UPEN via Coursea), Nutrition (Harvard Shool of Public Health) and functional medicine studies. Dr. Stanton is an avid sports fan, currently power weight lifting and kickboxing. For relaxation (yeah.. about a half minute each day), she paints and photographs and loves to spend time with her family of husband of 45 years, 2 sons and their wives, and 2 granddaughters.
Follow her on Twitter at: @MigraineBook, LinkedIn at https://www.linkedin.com/in/angelaastantonphd/ and facebook at https://www.facebook.com/DrAngelaAStanton/
My heart just skipped a beat while reading that you are working on a new book. Since finding your second edition (which I own in print and digital) my life has completely changed. I have gone from a migraine sufferer to a migraine boss. I used to carry an array of prescriptions in my purse and now I carry salt packets! I workout everyday and instead of falling asleep to the throbbing of my head, I peacefully listen to sleep sounds.I preach your research and recommendations to everyone in my life who will listen, migraineur or not. I appreciate your continued work and commitment to getting your knowledge out there so that migraine sufferers can get their life back. I pray medical professionals find you and wake up!
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Wow SLF, what a beautiful testimonial! ❤ Thank you!
Indeed, I am working on a book that is more nutrition-oriented but very specifically for migraine sufferers. It will detail–with the proper application–the low carbs high fat (LCHF), the ketogenic, and the carnivore (CD) ways of eating. Because we migraineurs are so different from other people, how we apply these ways of eating differs from how others apply it.
After this new book, I will update the Complete Guide book as well to the 3rd edition. 🙂
I am also being interviewed on a few YouTube videos and more is to come, in addition to a live presentation in May 2020 at the CarnivoryCon in Boulder, Colorado this year. More on that once I have all the links. I discuss there the carnivore diet and how to apply that to migraines.
I hope you will have a chance to attend the conference.
Best to you,
Hi Dr. Stanton – First, great work on everything you have done for people that suffer from migraines. I really learned a lot about migraines from the keto mojo blog post (I’m not a migraineur myself). I’m very intrigued by your use of the keto mojo for a version of a modified Kraft test. You mention that you use ketone level as proxy for insulin level. I have a keto mojo at home and I’m interested in trying to do it myself. Would you be willing to share how you map the values from ketone level to correspond to insulin level? Thank you!
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Thanks for your comment and your inquiry. The answer to your question will be fully provided in my new book–still working on the book so sometimes next year–hopefully early–but I can try to give a short synapses of what and how.
The first thing is the Kraft mimicking test. Kraft used a glucose (bg) and insulin test with oral glucose (OGTT) and measured it every hour for 5 hours. My test is slightly different. I use no OGTT, it is minimum 5 hours postprandial, and I measure blood ketones (BHB) instead of insulin. The total test is longer because i also request fasting and pre-meal test. In addition, I ask for the test every 30 minutes, not once an hour. And, finally, the postprandial part may go longer than 5 hours, depending on the last bg measurement. If the last measure in bg is lower than the pre-meal measure, the test needs to continue to be able to exclude a sugar crash–or to confirm one if it ends there–and also if the BHB goes too high (over 3).
The actual interpretation is complicated, because there are several variables that are unknown. In general, BHB should be opposing the movements of bg with a slight delay, though there are exceptions to this–those are the ones to look for. For example, assume you have 80 mg/dL for your bg and 1 mmol/L for BHB and then you eat an apple–just for conversation sake. Testing your bg will at first show a drastic increase and then returns to normal–perhaps even below what it was at the start, so reactive hypoglycemia. Because BHB is manufactured by the liver, there is a signal delay. So the glucose will already show up in your blood but BHB is still being made by your liver, up until the moment of insulin release. This delay will show an increase in BHB because your blood is already full of extra glucose, so organs that can use glucose will jump on the glucose to get it out of your blood.
This will show up as a short-term increase in BHB and then BHB will be flat-lined for some time.
So back to 80 mg/dL before apple and 100 mg/dL after the apple is eaten. BHB is at 1 mmol/L at the start. As your bg increases to 100 mg/dL, your BHB will increase to say 1.2 mmol/L and stay there for maybe 30-60 minutes, depending on how fast the glucose is taken out of your blood. Meaning the BHB will not be lost. Most people suggest that the apple will kick you out of ketosis. No, it won’t. It will stop your ketone production and use temporarily, but whatever BHB you already have in your system is preserved and will be used after the excess glucose is removed. As you bg returns to <=99 mg/dL, you will then start seeing BHB drop, say to 0.8 and then to 0.5 and then it will flat line for a bit or start to increase. When BHB drops is when your body switches back into using ketones again as fuel.
So, as you see, the pattern is complicated because you need to know what is consumed–I request the exact macros–how fast it is consumed, and need to understand the mechanics of bg and BHB.
In my new book I will have a section on this with example graphs and full explanation. This analysis is not easy if you only have you to examine, but I have done several hundreds and the pattern then reveals itself. I have also been examining my response to foods–I have close to 3000 bg and BHB measures recorded over the past few years with full diary of what I was doing. So the pattern emerged out of these many tests and I could finally see how misunderstood ketosis really is.
I hope this helps,