To The End!
Fighting for what science shows can harm your reputation, make you lose your job, and… who know how far they will go! This the story of Maryanne Demasi, Ph.D., an investigative science journalists:
“I became the subject of attacks by those with vested interests. Secret documents revealed food industry giants initiated ‘active defence’ against me (and others) for challenging their marketing messages.
It manifested in social media attacks, industry-sponsored propaganda by so-called ‘experts’ paid to undermine my credibility, critics’ calls for my sacking, and vexatious complaints about my scientific integrity.
Eventually, our entire team was axed from the ABC. The TV executives who promised to support us, the same people who approved and applauded our programs, were now the ones walking us all out the door.”
As always, things must be understood in context. The context here is revealing that statins don’t save lives. As we all know, many doctors are just too happy to prescribe statins. The pressure is on them by the pharmaceuticals as well as their pockets. Check if your doctor’s name is listed here, and if so, check how much money, lunches, dinners, “research funds” (clinical doctors don’t do research), etc., they have earned for the past 3 years. This database works for US doctors only–and be careful how you enter the name of your doctor. Enter only last name and state!!! Doctors have funny ways for evading discovery…!!
The Truth About Statins
If you only read one paper about statins, this is the one you should read in the BMJ (British Medical Journal). This academic paper reviewed all published statins clinical trials. Only 11 statin clinical trials included mortality information, so they only used those 11. Note: doctors are making “life-saving” or “life-destroying” decisions based on 11 small-scale clinical trials, and the world is go-gaga over statins, but do they have a reason to celebrate? This research paper presents an unbiased and professional research, comparing all findings available.
The goal of the research:
The researchers wanted to see the magnitude of the statistical significance in terms of long-term outcome to see if statins saved lives, and if so, by how much.
“Death was postponed between −5 and 19 days in primary prevention trials and between −10 and 27 days in secondary prevention trials. The median postponement of death for primary and secondary prevention trials were 3.2 and 4.1 days, respectively.”
When you see a negative number, as in -10, that actually means the those people died 10 days sooner than those not on statins. The average lifetime increase (after several years of statins use) is 3-4 days. not much to celebrate there after years of side effects!
What Is At Stake?
Millions and billions of dollars to the pharmaceutical companies and thousands (in some cases hundreds of thousands) of dollars in the pockets of statins prescribing doctors are at stake. At least, that how statin-supporter-doctors and big pharma see it, and why Dr. Demasi was fired. However, the real loser is YOU dear reader. Why? Because you pay however amount as your copay, you lose muscles, fracture bones, end up with cancer, lose your memory, get dementia and Alzheimer’s, Parkinson’s and a host of other diseases., lose your libido, end up with Viagra or similar to have sex, and in some cases, even destroy your heart–the very thing you want to save–by taking statins.
Most Common Adverse Effects
The most common adverse effects are headache, difficulty sleeping, flushing of the skin, tenderness, or weakness (myalgia), drowsiness, dizziness, nausea or vomiting, abdominal cramping or pain, bloating and gas, diarrhea, constipation, rash, muscle pain and damage, increased risk of diabetes mellitus, and liver damage. In a study over 5 years of statin treatments resulted in 75 cases of diabetes, 7.5 cases of bleeding stroke, and 5 cases of muscle damage per 10,000 people treated. Other adverse effects include neuropathy, pancreatic, liver, and sexual dysfunction.
Adverse events are more common in clinical practice than in randomized clinical trials. A systematic review concluded that clinical trial meta-analyses underestimate the rate of muscle pain associated with statin use. In some studies the rate of rhabdomyolysis is low. Rhabdomyolysis can result in life-threatening kidney injury. The risk of statin-induced rhabdomyolysis increases with age, use of other medications such as fibrates, and hypothyroidism.
There are some genetic variants that make this condition much more likely–though find a doctor who checks for your genetics before they prescribe statins. The gene SLCO1B1 (Solute carrier organic anion transporter family member 1B1) codes for an organic anion-transporting polypeptide that is involved in the regulation of the absorption of statins. A rather common variant in this gene can significantly increase the risk of myopathy and rhabdomyolysis.
I find it interesting that of the number of people I know who are on statins, two are cases of rhabdomyolysis–so it cannot be that rare… food for thought.
Coenzyme Q10 (ubiquinone) production is blocked by statin use.
There are many reports of cognitive impairment with statins but their reporting is mixed. The FDA package insert on statins includes a warning about the potential for possibly reversible cognitive effects. While some research show minimal cognitive effects, some show confused effects, others, particularly case studies, show major cognitive effects.
My personal experience with those taking statins, is a general consistency with the case studies: cognitive decline for all people I know who take statins. In fact, other than muscle aches and pains, memory loss is the most frequently heard complaint. There is also an inverse relationship between LDL and ageing. Meaning, as we get older, a higher LDL is actually to our benefit, so reduced LDL is to our detriment, and causes shorter lives.
Use of statins is associated with an increased risk in developing type 2 diabetes. In fact, it may double the risks. Statins reduce glycemic control. Statins are thought to decrease the cells’ uptake of glucose from the bloodstream. One way this is thought to occur is by interfering with cholesterol synthesis (duh moment) which is necessary for the production of proteins responsible for glucose uptake into cells, such as GLUT1.
There are many studies that find connection between statins use and cancer, such as breast cancer. In general, it is likely not statins themselves that cause cancer but rather their lowering of LDL. There appears to be an inverse correlation between LDL and cancer risk. And that is because LDL has a beneficial role in helping our immune system to remove pathogens and harmful cells–meaning it is part of our immune system we reduce when we reduce LDL. In addition, LDL is the carrier of all fat-soluble vitamins and minerals. By blocking all these essential vitamins and minerals, our cancer-prevention-power is reduced, and our general health is compromised. So statins may be indirectly associated with increased cancer rates, weakened immune system, weakened body and mind, and vitamin and mineral deficiencies.
So what is really at stake? Your health! Your life! Your money! Your future! Pay attention! Don’t let yourself be trapped. Understand the possible outcome–3-4 days of increase in lifespan–and match that with the possible negative experiences–as listed in the long list of side effects.
As for Dr. Maryanne Demasi: being fired for a job so well done that a company’s livelihood became at stake, and this revealed their corruption, is a testament of your success and achievement. You have become a power to recon with. Congratulations!
Your comments are welcome, as always, and are moderated for appropriateness.