One more misleading article

The image shows how cardiovascular disease is not associated with high cholesterol, yet the article concluded that high cholesterol causes coronary cardiovascular events.

coronary artery disease cause

coronary artery disease cause

 

 

 

Yellow highlighting is mine to show what actually does contribute to cardiovascular events.

How strange that scientists have to conclude the opposite of what their data shows to be able to publish!

About Angela A Stanton, Ph.D.

Angela A Stanton, PhD, is a Neuroeconomist focusing on chronic pain--migraine in particular--physiology, electrolyte homeostasis, nutrition, and genetics. She lives in Southern California. Her current research is focused on migraine cause, prevention and treatment without the use of medicine. As a forever migraineur from childhood, her discovery was helped by experimenting on herself. She found the cause of migraine to be at the ionic level, associated with disruption of the electrolyte homeostasis, resulting from genetic variations of all voltage dependent channels, gates, and pumps that modulate electrolyte mineral density and voltage in the brain. In addition, insulin and glucose transporters, and several other variants, such as MTHFR variants of B vitamin methylation process and many others that are different in the case of a migraineur from the general population. Migraineurs are glucose sensitive (carbohydrate intolerant) and should avoid eating carbs as much as possible. She is working on her hypothesis that migraine is a metabolic disease. As a result of the success of the first edition of her book and her helping over 4000 migraineurs successfully prevent their migraines world wide, all ages and both genders, and all types of migraines, she published the 2nd (extended) edition of her migraine book "Fighting The Migraine Epidemic: Complete Guide: How To Treat & Prevent Migraines Without Medications". The 2nd edition is the “holy grail” of migraine cause, development, and prevention, incorporating all there is to know. It includes a long section with for medical and research professionals. The book is full of academic citations (over 800) to authenticate the statements she makes to be followed up by those interested and to spark further research interest. It is a "Complete Guide", published on September 29, 2017. Dr. Stanton received her BSc at UCLA in Mathematics, MBA at UCR, MS in Management Science and Engineering at Stanford University, PhD in NeuroEconomics at Claremont Graduate University, fMRI certification at Harvard University Medical School at the Martinos Center for Neuroimaging for experimenting with neurotransmitters on human volunteers, certification in LCHF/ketogenic diet from NN (Nutrition Network), currently working on her certification in physiology, and functional medicine. Dr. Stanton is an avid sports fan, currently power weight lifting and kickboxing. For relaxation (yeah.. about a half minute each day), she paints and photographs and loves to spend time with her family of husband of 44 years, 2 sons and their wives, and 2 granddaughters. Follow her on Twitter at: @MigraineBook, LinkedIn at https://www.linkedin.com/in/angelaastantonphd/ and facebook at https://www.facebook.com/DrAngelaAStanton/
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12 Responses to One more misleading article

  1. chris c says:

    http://sci-hub.tw/10.1016/j.ahj.2008.08.010

    yet to read it

    Yes I’ve read numerous similar articles which find no link between LDL and CVD and thus conclude that that is because the LDL has not yet been lowered enough. Probably if they didn’t write that they would not have been published.

    You probably know EPIC-Norfolk

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC26599/

    and other articles like

    http://sci-hub.tw/10.1111/j.1464-5491.2008.02581.x

    http://care.diabetesjournals.org/content/diacare/31/6/1144.full.pdf

    which find a clear and linear relationship between HbA1c and CVD or premature death. I’d love to know how “cholesterol” gets the blame for this.

    Now off to read Malcolm Kendrick’s latest episode

    https://drmalcolmkendrick.org/2018/11/27/what-causes-heart-disease-part-59/

    it seems the answer is “just about everything except LDL”

    Liked by 1 person

    • I will write more about it only I have so many things to do that sinking deeper into stuff to do… This article concluded different. It concluded that the low HDL may be a problem–and indeed they are right in that since the LDL in this study was all within the range recommended.

      However, the study ignored the higher correlation with T2D, HbA1c, etc., etc., etc. People were also smoker.. duh…

      I love Malcolm.. “suchlike” is my favorite term. 😉

      Like

      • chris c says:

        Yes and they pretty much ignored trigs. Of course we know a pretty foolproof way to raise HDL and drop trigs through the floor but that doesn’t sell any drugs, or manufactured foodlike substances. All the drugs so far used to increase HDL have done so but not affected health. Then there’s this

        “Cholesterol levels in patients with CAD have declined
        since the 1960s, first markedly, and in more recent years
        in a more gradual fashion.”

        They look but do not see.

        Thanks to Medical twitter

        Serum Cholesterol and Atherosclerosis in Man

        https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.23.6.847

        “In the present study, we did not find any
        significant correlation between the blood serum
        total cholesterol and atherosclerotic index
        as a representation of the extent and severity
        of atherosclerosis for any of the vessels studied.”

        from 1961

        I can remember a clueful consultant back in the eighties telling me when they saw high “cholesterol” they would assume thyroid and do a TSH, way back before metabolic syndrome was even invented. Then the link was broken.

        Did you have your medical yet? I predict they looked for drug deficiencies and found you lacking in statins among others, probably also BP meds and PPIs. Are you old enough for alendronic acid yet?

        Liked by 1 person

        • hahahahah did I ever have my physical yet! I think my doctor will need to be brought to. We were estimating that my LDL will go up (even I thought it may since I now eat only animal products and fats) and it went down!! Hahahha.. My trig was already low and it went lower and my HDL that was already higher than required went even higher. All my inflammation markers went down, glucose and HbA1c normal; B vitamins normal.. apparently it takes them a very long time to get vitamin D figured out–still waiting for that results. I never had a better looking blood test. I can go back up to 20 years on my medical records online and this is the best test I have had in that period.

          Yeah, just about 1961 as the last year when descent research was still allowed to publish. After that only papers that supported Ancel keys hypothesis could be published so not surprised. At that time they truly believed what they wrote and didn’t realize the statistical and hypothetical errors. Now it is just all about the money.

          Do you know that the AHA now wants CAC to be a routine testing and if the score is 0 to not give statins??? https://www.heart.org/en/news/2018/11/13/coronary-calcium-test-could-help-clarify-heart-disease-risk-and-control-cholesterol?fbclid=IwAR1d1O8-Qi-tHy8IP70KOhW1rOQNwEvMUxzaAeIFjh3SlJgalA5_jPRU034

          Like

        • chris c says:

          Well that’s what happens when you METABOLISE what you eat rather than having stuff hanging around in the bloodstream awaiting processing!

          Yes some early papers are worth reading, the likes of George Henderson and Tucker Goodrich have dug out a few. That one actually came from Tom Naughton, my bad!

          Another thing I miss, the likes of Gerald Reaven (most of his papers are still paywalled but you can find them on Sci-Hub) used to plot individual subjects’ responses rather than tweak them into a statistical mish-mash, For example you can see most subjects have a similar response with differing amplitude, then one or two who zing off in a different direction. Modern researchers would undoubtedly exclude the “outliers”.

          Yes my vitamin D took a few weeks to come back – it was 95! You should have seen my doctor’s face when I said

          “Oh, that’ll be all the grass fed butter and cheese then!”

          Bless her, it’s taken her about a decade to come on board with what I’ve been doing. A while back she said

          “By now we would have expected you to be on two or three diabetes medications”

          she went on to say

          “You’re twenty years ahead of your time!”

          I hadn’t the heart to tell her actually I was about fifty years BEHIND the times. The last diabetics who were put on low carb by default are now dying, of old age not complications. Soon, like us folks who remember a time before there were “epidemics” of obesity, diabetes and other metabolic diseases will be dead too, then it will be as if we never existed,

          I remember back when William Davis’ use of CAC was considered controversial, so I suppose this is progress.

          Liked by 1 person

        • Indeed. Max Planck said something like it takes a generation of scientists to die out before a new idea becomes accepted but I think he was wrong. In nutrition it takes 2-3 generations of scientists. I was just thinking about it yesterday: what kind of trash food would I get today if I ended up in a senior care somewhere? And I am old enough to know that I will be getting trash when I get to a nursing home… I hope to die on day one there from a stroke or something… maybe starve myself. There is no way I will put any junk ever in my mouth without throwing up. And I agree to your 50 years behind… maybe even more. Shame that all that good science was wasted.

          Like

        • chris c says:

          It’s scary how the young ones are still infected by the lipid hypothesis, cholesterol hypothesis etc. and take them as gospel. My doctor may have changed her views, along with a small but increasing number of others, but I have no doubt when I am dead Dr Evidence Based Macho Man will say

          “See? We told him fifteen years ago that dangerous low carb diet would kill him!” ignoring the fact that if I had continued eating what I was told I would be massively fat, on a whole bunch of drugs and with fewer than the average number of limbs – because that is what is meant to happen.

          I’ve noticed a few dieticians indignantly protesting that they never condemned low carb diets but the effect is spoiled by their many colleagues who continue to do just that. And people leaving dietician training in disgust at what they are expected to parrot to pass their exams.

          It scares me too to think what I will be fed in hospital or care – high carb low fat low protein processed crap-in-a-bag. I literally don’t want to live that long.

          And in other news, Malcolm Kendrick is removed from Wikipedia just as new recommendations for statins emerge, Britvic makes a major donation to Diabetes UK and the NHS announces “diabetes reversal” treatment using a starvation diet of chemical-laden high carb shakes “but they’re vegan” . . .to celebrate I just ate lamb’s liver and bacon with a giant mushroom, Brussels sprouts and two thickly buttered oatcakes. Not many carbs slaughtered there then.

          Liked by 1 person

        • Oat cakes??? You eat oats? That’s grain. 😦 I don’t go near anything like that.

          You are totally right about the major major disgusting confusion about nutrition–and why some people turn away from being nutritionists. I considered adding that to my PhD and interviewed the association with respect to residency requirements. And yep, I would have to lie!!! I would have to tell kidney and cancer patients and T2Ds to eat carbs though I know it harms them. I would have no option. I decided to not get that added to my degrees. Lying is not my kind of enhanced work…

          I heard about the Wikipedia on twitter from Zoe. Are we connected there? I am @MigraineBook I stopped donating to Wikipedia and wrote them an email response to the request instead.

          Eek about that shake!!! Not even ethical for a lab rat. 😦

          Like

        • chris c says:

          Relax! My oatcakes are only about 5g carbs and contain no wheat. They are useful to hold up my grass-fed butter, cheese, smoked salmon etc. I sometimes eat other grains too, I probably get through a kilo of rice and half that of quinoa in a year – I use them to soak up the fatty juices from my stir-fries, curries etc. Anatomically correct portions! Nothing like what I used to eat or what we are told to eat. Think hormesis.

          I read Twitter but don’t post, or I would have no life.

          https://drmalcolmkendrick.org/2018/12/03/dr-malcolm-kendrick-deletion-from-wikipedia/

          some of the replies by “WIkipedia Editor” and its friends are enlightening, as is some of their discussion on Wikipedia itself. I see Uffe Ravnskov has now also been deleted and they are attacking Richard Feinman. Maybe they should delete Richard Feynman too

          “I would rather have questions that cannot be answered than answers that cannot be questioned”

          meanwhile

          https://infogalactic.com/info/Malcolm_Kendrick

          been looking around, this seems less censored and biased than Wikipedia. I will also be emailing Wikipedia explaining why I will NEVER donate any money again.

          Liked by 1 person

        • wow, so many responses! Malcolm closed off comments now but I just watched the TED talk on Astroturf… excellent! https://www.youtube.com/watch?v=-bYAQ-ZZtEU Yes, I bumped into my own share of problems with Wikipedia and refuse to donate.. I hop they get wiped off the planet though that is not likely to happen. Maybe I should write a blog article about that 😉

          Like

  2. Kim says:

    Thank you for sharing this!

    Liked by 1 person

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